Results 211 to 220 of about 196,851 (322)

Establishment of X chromosome inactivation and epigenomic features of the inactive X depend on cellular contexts [PDF]

, 2016
Céline Vallot, Jean‐François Ouimette, Claire Rougeulle   +2 more
openalex   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Distributed X chromosome inactivation in brain circuitry is associated with X-linked disease penetrance of behavior [PDF]

Eric R Szelenyi, Danielle Fisenne, Joseph E. Knox, Julie A. Harris, James Gornet, Ramesh Palaniswamy, Yongsoo Kim, Kannan Umadevi Venkataraju, Pavel Osten   +8 more
openalex   +1 more source

The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome Inactivation

Cell, 2010
D. Tian, Shan Sun, Jeannie T. Lee
semanticscholar   +1 more source

In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini, Simona Saporiti, Crescenzo Coppa, Mara Rossi, Fabio Centola, Alessandro Arcovito   +5 more
wiley   +1 more source

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

Rare Metals, EarlyView.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu, Ding‐Hu Zhang, Chuan Hu, Yi‐Nan Ding, Kun Chen, Yi Jiang, Jun Luo, Fei Cao, Wei‐Yuan Hao, Bin‐Yan Zhong, Jie Lin, Dong Xu, Jia‐Ping Zheng   +12 more
wiley   +1 more source

Breaking rules: the complex relationship between DNA methylation and X-chromosome inactivation in the human placenta. [PDF]

Biol Sex Differ
Inkster AM, Matthews AM, Phung TN, Plaisier SB, Wilson MA, Brown CJ, Robinson WP.   +6 more
europepmc   +1 more source

Complexities of X chromosome inactivation status in female human induced pluripotent stem cells—a brief review and scientific update for autism research [PDF]

, 2016
Mary G. Dandulakis, Kesavan Meganathan, Kristen L. Kroll, Azad Bonni, John N. Constantino   +4 more
openalex   +1 more source

A multimodal deep learning framework for predicting sunitinib response in advanced clear cell renal cell carcinoma

VIEW, EarlyView.
In this study, we constructed a prognostic model for ccRCC patients treated with Sunitinib through a deep learning‐based multimodal approach. Our CGPR model further confirms the feasibility of integrating multimodal and provides guidance for future tumor patients to receive precision therapy.
Xi Tian, Yuchen Jiang, Shuxuan Zhu, Xiaohang Liu, Aihetaimujiang Anwaier, Shiqi Ye, Kun Chang, Yuanyuan Qu, Ya‐Jia Gu, Hailiang Zhang, Dingwei Ye, Wenhao Xu   +11 more
wiley   +1 more source

Supplementary Material for: De novo Interstitial Triplication of MECP2 in a Girl with Neurodevelopmental Disorder and Random X Chromosome Inactivation

, 2011
Sonia Mayo, Sandra Monfort, Mónica Rosello, Carmen Orellana, Silvestre Oltra, Judith Armstrong, Vicenç Català, Francisco Martı́nez   +7 more
openalex   +1 more source