Results 201 to 210 of about 92,054 (252)

G-quadruplex folding in Xist RNA antagonizes PRC2 activity for stepwise regulation of X chromosome inactivation. [PDF]

Mol Cell
Lee YW, Weissbein U, Blum R, Lee JT.
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Distributed X chromosome inactivation in brain circuitry is associated with X-linked disease penetrance of behavior. [PDF]

Cell Rep
Szelenyi ER, Fisenne D, Knox JE, Harris JA, Gornet JA, Palaniswamy R, Kim Y, Venkataraju KU, Osten P.   +8 more
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Unfavorable switching of skewed X chromosome inactivation leads to Menkes disease in a female infant. [PDF]

Sci Rep
Matsumoto A, Kano S, Kobayashi N, Matsuki M, Furukawa R, Yamagishi H, Yoshinari H, Nakata W, Wakabayashi H, Tsuda H, Watanabe K, Takahashi H, Yamagata T, Matsumura T, Osaka H, Mori H, Iwamoto S.   +16 more
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X Chromosome Inactivation and Autoimmunity

Clinical Reviews in Allergy and Immunology, 2009
Autoimmune diseases appear to have multiple contributing factors including genetics, epigenetics, environmental factors, and aging. The predominance of females among patients with autoimmune diseases suggests possible involvement of the X chromosome and X chromosome inactivation.
Wesley Brooks
exaly   +3 more sources

Digging into X chromosome inactivation

Science, 2021
Characterizing X chromosome inactivation in nonhuman primates reveals some ...
Rougeulle, C., Heard, Edith
openaire   +3 more sources

Regulation of X-chromosome inactivation by the X-inactivation centre

Nature Reviews Genetics, 2011
X-chromosome inactivation (XCI) ensures dosage compensation in mammals and is a paradigm for allele-specific gene expression on a chromosome-wide scale. Important insights have been made into the developmental dynamics of this process. Recent studies have identified several cis- and trans-acting factors that regulate the initiation of XCI via the X ...
Sandrine Augui, Elphège P. Nora, Edith Heard   +2 more
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Mechanisms of X-chromosome inactivation

Frontiers in Bioscience, 2006
Mammalian X-chromosome inactivation is an impressive example of epigenetic gene regulation, whereby the majority of genes on the approximately 160 Mb X chromosome are silenced in a strictly cis-limited fashion. In this review we will discuss the important players involved in the silencing process.
Samuel C, Chang, Tracy, Tucker, Nancy P, Thorogood, Carolyn J, Brown   +3 more
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X-CHROMOSOME INACTIVATION IN MAMMALS

Annual Review of Genetics, 1997
▪ Abstract  The inactive X chromosome differs from the active X in a number of ways; some of these, such as allocyclic replication and altered histone acetylation, are associated with all types of epigenetic silencing, whereas others, such as DNA methylation, are of more restricted use. These features are acquired progressively by the inactive X after
E, Heard, P, Clerc, P, Avner
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Inactivation of the X-Chromosome

New England Journal of Medicine, 1972
IN its classic form, the hypothesis of X-chromosome inactivation holds that only one of the two X-chromosomes present in cells of female mammals is functional. The "decision" of which X-chromosome is to operate in a cell occurs quite early in embryogenesis and, once made, is irreversible for that cell and all its progeny.
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