Study on the processing transformation law of CATR and ATR in Xanthii Fructus and the metabolomics mechanism of their transformation products in LO2 cells [PDF]
Background: The thermal processing of Xanthii Fructus is known to attenuate its hepatotoxicity. Carboxyatractyloside (CATR) and atractyloside (ATR), the primary toxic constituents, exhibit differential toxicity, with CATR being more potent.
Lingling Wang +5 more
doaj +2 more sources
Integrating multi-omics, network pharmacology, and experimental validation to unveil the molecular mechanisms of Fructus Xanthii in treating asthma [PDF]
IntroductionThis study employs an integrated approach combining multi-omics analysis, network pharmacology, machine learning, and experimental validation to elucidate the molecular mechanisms of Fructus Xanthii (Chinese name: Cang-Er-Zi) in treating ...
Yiqun Dong +11 more
doaj +2 more sources
Quality Evaluation of Traditional Chinese Medicine Prescription in Naolingsu Capsule Based on Combinative Method of Fingerprint, Quantitative Determination, and Chemometrics. [PDF]
Background. Naolingsu capsule (NLSC) is a well‐known traditional Chinese medicine (TCM) prescription in China. It is widely used to treat neurasthenia, insomnia, cardiovascular and cerebrovascular disease, and other diseases. However, its inalienable chemical groups have not been carried out. Methods.
Xu L +9 more
europepmc +2 more sources
Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet. [PDF]
Fructus Xanthii (FX) has been widely used as a traditional herbal medicine for rhinitis, headache, cold, etc. Modern pharmacological studies revealed that FX possesses anti-inflammatory, anti-oxidative, and anti-hyperglycemic properties.
Xiumin Li +8 more
doaj +5 more sources
Effect of Traditional Chinese Medicine on Allergic Rhinitis in Children under Data Mining.
The data mining analysis of the medication rule and the curative effect of traditional Chinese medicine in treating allergic rhinitis in children was performed by using the association rule Apriori algorithm. The model of interest degree was introduced to improve the Apriori algorithm, and the performance difference of the algorithm before and after ...
Shen M, Liu J, Wang K.
europepmc +2 more sources
Clinical Efficacy of Tuomin Zhiti Decoction in Allergic Rhinitis.
Allergic rhinitis (AR) is a noninfectious inflammatory disease seriously affecting the quality of life. This study aimed to assess the efficacy of the Tuomin Zhiti decoction in allergic rhinitis and to provide a reference for clinical treatment. One hundred patients with AR treated in the Department of Otolaryngology of our hospital from January 2019 ...
Zhang JX, Wang WY.
europepmc +2 more sources
Objective. To conduct a systematic review on the mechanism of action and use of traditional Chinese medicines (TCM) in allergic rhinitis treatment. Background. Allergic rhinitis (AR) is a type I allergic disease of the immune system induced by immunoglobulin E mediated inflammation and is characterized by sneezing, nasal itching, paroxysmal nasal ...
Mao D +6 more
europepmc +2 more sources
Phytochemical Analysis on Quantification and the Inhibitory Effects on Inflammatory Responses from the Fruit of Xanthii fructus. [PDF]
Xanthii fructus (Compositae) is a traditional herbal medicine used for treating headache, toothache, pruritus, empyema, and rhinitis. In this study of the quality control of X. fructus, we performed simultaneous analysis of nine marker compounds: Protocatechuic acid (1), chlorogenic acid (2), caffeic acid (3), 4,5-dicaffeoylquinic acid (4), ferulic ...
Yoo SR +4 more
europepmc +4 more sources
Revisiting traditional Chinese materia medica from European historical collections and perspective for current use. [PDF]
Background and aim: Chinese Materia Medica (CMM) is subject to changes over time. Investigating changes in botanical ingredients, applications, plant parts used as well as name changes over time, contribute to the understanding of the history and ...
Jia Y, Wang M, van Andel T.
europepmc +3 more sources
In this research study, we will study the clinical effect of Biyuan Tongqiao granules with saline nasal irrigation for treatment of chronic sinusitis. It will also study its impacts on the computed tomography (CT) score of the nasal sinus and negative reactions in patients.
Ma F, Xu L, Ai P.
europepmc +2 more sources

