Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis. [PDF]
Evid Based Complement Alternat Med, 2022 Chronic rhinosinusitis (CRS) is a complex condition brought on for many reasons, and its prevalence is rising gradually around the world. Xanthii Fructus (XF) has been used in the treatment of CRS for decades and is effective.
Ding S +5 more
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Processed Xanthii fructus increases cell viability of mast cell line, RBL-2H3
Oriental Pharmacy and Experimental Medicine, 2004 The effect of aqueous extract of processed Xanthii fructus (PXF) on cell viability and histamine release from mast cell has been investigated. PXF showed higher cell viability than unprocessed Xanthii fructus (XF) at the concentrations of 5 and 10 mg/ml.
Seung-Heon Hong +7 more
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Integrating multi-omics, network pharmacology, and experimental validation to unveil the molecular mechanisms of Fructus Xanthii in treating asthma [PDF]
Frontiers in PharmacologyIntroductionThis study employs an integrated approach combining multi-omics analysis, network pharmacology, machine learning, and experimental validation to elucidate the molecular mechanisms of Fructus Xanthii (Chinese name: Cang-Er-Zi) in treating ...
Yiqun Dong +11 more
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Prediction of the targets of the main components in blood after oral administration of Xanthii Fructus: a network pharmacology study. [PDF]
RSC Adv, 2018 Xanthii Fructus (XF), a famous traditional Chinese medicine (TCM), has been widely used in the treatment of rhinitis and other diseases. However, the targets of the main XF components found in the blood after oral administration of XF extract are still ...
Zhuang Y +5 more
europepmc +2 more sources
Stir-baked Xanthii fructus ameliorates adjuvant arthritis by regulating gut microbiota, short-chain fatty acids and metabolites [PDF]
Frontiers in MicrobiologyIntroductionRheumatoid arthritis (RA) is a common and widespread autoimmune disease whose incidence is increasing. Stir-baked Xanthii fructus (XF) is used to treat RA in clinic. However, it’s in vivo efficacy and mechanistic pathways remain unclear. This
Xinyuan Cui +8 more
doaj +2 more sources
Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet. [PDF]
PLoS ONE, 2013 Fructus Xanthii (FX) has been widely used as a traditional herbal medicine for rhinitis, headache, cold, etc. Modern pharmacological studies revealed that FX possesses anti-inflammatory, anti-oxidative, and anti-hyperglycemic properties.
Xiumin Li +8 more
doaj +5 more sources
Phytochemical Analysis on Quantification and the Inhibitory Effects on Inflammatory Responses from the Fruit of Xanthii fructus. [PDF]
Pharmacogn Mag, 2015 Xanthii fructus (Compositae) is a traditional herbal medicine used for treating headache, toothache, pruritus, empyema, and rhinitis. In this study of the quality control of X. fructus, we performed simultaneous analysis of nine marker compounds: Protocatechuic acid (1), chlorogenic acid (2), caffeic acid (3), 4,5-dicaffeoylquinic acid (4), ferulic ...
Yoo SR +4 more
europepmc +4 more sources
Journal of EthnopharmacologyETHNOPHARMACOLOGICAL RELEVANCE As a natural medicine, Xanthii Fructus (XF) is widely used in traditional Chinese medicine (TCM) and Tibetan medicine. It has been demonstrated to alleviate allergic rhinitis (AR) in modern research.
Xianli Meng, Hai Zhang
exaly +2 more sources
Integrated network pharmacology and molecular docking reveal multi-target hepatotoxic mechanisms of Xanthii fructus. [PDF]
Medicine (Baltimore)Xanthii fructus (XF), a traditional Chinese medicine, is commonly used for anti-inflammatory and analgesic purposes; however, its hepatotoxicity limits its use to some extent and the underlying mechanisms remain unclear. The present study aimed to explore the key targets and molecular pathways of XF-induced liver injury through an ...
Fu X, Xiong F, Lin X, Lin Z, Jiang X.
europepmc +4 more sources
Xanthii fructus inhibits malignant behaviors of lung cancer cells
Infection International, 2018 Abstract Objective This study aimed to investigate the influence of Xanthii fructus on the expression of small noncoding RNA (sncRNA) and the malignant behaviors of lung cancer cells. Method A549 cells were treated with Xanthii fructus extract. SncRNA expression was detected by real-time PCR.
Wang Zhen-fei +4 more
openaire +2 more sources