Integrated network pharmacology and molecular docking reveal multi-target hepatotoxic mechanisms of Xanthii fructus. [PDF]
Xanthii fructus (XF), a traditional Chinese medicine, is commonly used for anti-inflammatory and analgesic purposes; however, its hepatotoxicity limits its use to some extent and the underlying mechanisms remain unclear. The present study aimed to explore the key targets and molecular pathways of XF-induced liver injury through an ...
Fu X, Xiong F, Lin X, Lin Z, Jiang X.
europepmc +4 more sources
Xanthii Fructus (XF) is widely used in traditional anti-bacterial and anti-inflammatory Asian medicine. Allergic rhinitis is a common inflammatory disease characterized by markedly increased levels of anti-inflammatory factors and the recruitment of inflammatory cells into the nasal mucosa.
Gwak NG +10 more
europepmc +4 more sources
Developments in the study of Chinese herbal medicine's assessment index and action mechanism for diabetes mellitus. [PDF]
The endocrine disorder diabetes mellitus (DM) is a global phenomenon significantly influencing human health. Traditional Chinese medicine (TCM), with its long history, has been treating diabetes for over two millennia. The main types of animal used to model diabetes are rodents, zebrafish and primates.
Liu XY +5 more
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A case of acute liver and kidney failure caused by Xanthii Fructus
病例资料患者,女,31岁,因"服用苍耳子20 d,恶心呕吐4 d"于2017年12月23日入院。患者20 d前因采用偏方治疗鼻窦炎,冲水服用磨成粉末的苍耳子,每日1次,服用20 d,共约250 g。4 d前出现恶心呕吐,随后出现精神差,神志淡漠,伴尿量减少,每天约200~400 mL。既往鼻窦炎病史,无肝肾疾病病史。查体:T 36℃,P 65次/min,R 14次/min,BP 126/85 mmHg,神志淡漠,精神差 ...
LUAN Hong +5 more
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Preparative separation of seven phenolic acids from Xanthii Fructus using pH-zone-refining counter-current chromatography combined with semi-preparative high performance liquid chromatography [PDF]
Lihua Xu, Xinming Wang, Jia Li
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Processed Xanthii fructus increases cell viability of mast cell line, RBL-2H3
The effect of aqueous extract of processed Xanthii fructus (PXF) on cell viability and histamine release from mast cell has been investigated. PXF showed higher cell viability than unprocessed Xanthii fructus (XF) at the concentrations of 5 and 10 mg/ml.
exaly +3 more sources
Phytochemicals & Pharmacological activity of Xanthium strumarium: An Updated Review [PDF]
Therapeutic plants are of extraordinary worth in the field of treatment and fix of infections. Throughout the long term, logical examination has extended our insight into the compound constituents of the therapeutic plants, which decide the restorative ...
Gupta, Vishal +3 more
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Background. With the widespread use and abuse of antimicrobial drugs, the problem of bacterial resistance is becoming increasingly prominent. The clinical detection rate of drug‐resistant bacteria is increasing year by year, so there is an urgent need to develop new antimicrobial drugs.
Siyuan Lv +10 more
wiley +1 more source
The fruits of Xanthium sibiricum Patr: A review on phytochemistry, pharmacological activities, and toxicity [PDF]
In recent years, drug development and research have gradually shifted from chemical synthesis to biopharmaceutical and natural drugs. Natural medicines, such as traditional Chinese medicine, have been among the first studied because of their long ...
Agata +109 more
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Tibetan Medicines and Tibetan Prescriptions for the Treatment of Diabetes Mellitus
Diabetes mellitus (DM) is one of the most serious diseases threatening human health and because of that, it is imperative to look for drugs to tackle it. The Tibetan medicine, a traditional medical system used in China, is currently being the focus of research towards the discovery of new effective drugs against several diseases.
Jie Gao +7 more
wiley +1 more source

