Results 101 to 110 of about 112,529 (303)

A Review on Xanthine Oxidase-Based Electrochemical Biosensors: Food Safety and Quality Control Applications

open access: yesChemosensors
Electrochemical biosensors are integrated bio-receptor–transducer devices that convert specific biological interactions into measurable electrical signals.
Totka Dodevska
doaj   +1 more source

Synthesis, physical and chemical properties of 7-methylxanthine derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
It is known that 8-aminosubstituted N-methylated xanthines are dipeptidyl peptidase-4 antagonists, ligands for 5-hydroxytryptamine receptors and exert diverse biological effects.
M. I. Romanenko   +3 more
doaj   +1 more source

Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012 [PDF]

open access: yes, 1999
The detection superoxide production in vascular cells is usually limited by a low sensitivity of available assays, We tested the applicability of the luminol derivate L-012 {[}8-amino-5-chloro-7-phenylpyridol{[}3,4-d]pyridazine-l,4(2H,3H)dione] to ...
Gloe, Torsten   +4 more
core   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Assessment of purine catabolism and morbidity in miners depending on their work experience

open access: yesRussian Open Medical Journal
Objective — The role of end products of purine metabolism as predictors of the development of pathological changes and diseases caused by the impact of dust on the human body in a professional environment vs.
Diana M. Shaukhat   +6 more
doaj   +1 more source

Identification of YdhV as the first molybdoenzyme binding a Bis-Mo-MPT cofactor in escherichia coli [PDF]

open access: yes, 2019
The oxidoreductase YdhV in Escherichia coli has been predicted to belong to the family of molybdenum/tungsten cofactor (Moco/Wco)-containing enzymes. In this study, we characterized the YdhV protein in detail, which shares amino acid sequence homology ...
Dau, Holger   +7 more
core   +1 more source

Clinical and social aspects of dysmenorrhea development

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Modern antibiotics and synthetic antimicrobial agents play a leading role in the treatment of bacterial infections. Despite their effectiveness, they cause a number of side effects, and thus the search for new antimicrobial and antifungal agents is ...
O. P. Dolhikh   +4 more
doaj   +1 more source

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang   +7 more
wiley   +1 more source

Synthesis and physical-chemical properties of 8-benzylidenhydrazino-1-(4-fluorobenzyl)theobromine derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
The aim of the work is thesynthesis and research of physical and chemical properties of earlier undescribed 1,8-disubstituted of theobromine, which are potential biologically active compounds.
D. G. Ivanchenko   +3 more
doaj   +1 more source

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