Results 101 to 110 of about 89,320 (324)

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Studies on Xanthine Oxidase [PDF]

open access: green, 1924
Malcolm Dixon, Sylva Thurlow
openalex   +1 more source

Guidelines for Studying the Oxidative Stress Damage Model on Drosophila melanogaster

open access: yesFuture Postharvest and Food, EarlyView.
This guideline introduced Drosophila as a research model to summarize in detail the research methods of indicators that can characterize oxidative stress. It generally includes four aspects such as generation of ROS, damage caused by ROS, antioxidant defense, and cell stress repair and apoptosis.
Quanyong Wu
wiley   +1 more source

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants

open access: yesGlobal Challenges, EarlyView.
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu   +3 more
wiley   +1 more source

Inhibition of Xanthine Oxidase Activity by Ethanolic Extract of Piperomia pellucida L., Acacypha indica L. and Momordica charantia L.

open access: yesIndonesian Biomedical Journal, 2016
BACKGROUND: Uric acid is a final result of purine catabolism, the enzymatic reactions in the body cells from amino acids or ribonucleotide dinucleotide. Peperomia pellucida L. (P. pellucida), Acalypha indica L. (A. indica) and Momordica charantia L.
Parawansah Parawansah   +3 more
doaj   +1 more source

Screening of methanol extracts of sixty plants from Kerman for their potential xanthine oxidase inhibitory activity [PDF]

open access: yesJournal of HerbMed Pharmacology, 2017
Introduction: Gout is a chronic metabolic disease in which xanthine oxidase plays a crucial role. Many natural compounds such as various flavonoids have been reported to have inhibitory effect on xanthine oxidase.
Ahmad Gholamhoseinian   +2 more
doaj  

Ultra-rapid, Quantitative, Label-free Antibiotic Susceptibility Testing via Optically Detected Purine Metabolites [PDF]

open access: yesarXiv
There is an urgent need for the development of novel and truly rapid (equal or less than 1 hour) antibiotic susceptibility testing (AST) platforms in order to provide best antimicrobial prescribing practices and to help reduce the increasing global threat of antibiotic resistance.
arxiv  

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang   +7 more
wiley   +1 more source

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