Results 91 to 100 of about 75,914 (267)

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

Phytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao, Alimu Tulahong, Xinlu Xu, Tiemin Jiang, Ruiqing Zhang, Yanze Lin, Zhongdian Yuan, Rexiati Ruze, Yingmei Shao   +8 more
wiley   +1 more source

Computational Studies Of Natural Flavonoids Towards The Discovery Of A Potential Xanthine Oxidase Inhibitor. [PDF]

, 2008
Xantina oksidase (XO) memangkinkan penukaran hipoxantina kepada xantina dan seterusnya xantina kepada asid urik. Xanthine oxidase (XO) catalyses the conversion of hypoxanthine to xanthine and subsequently xanthine to uric ...
Mohammad Alnajjar, Belal Omar
core   +1 more source

Clinical and social aspects of dysmenorrhea development

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Modern antibiotics and synthetic antimicrobial agents play a leading role in the treatment of bacterial infections. Despite their effectiveness, they cause a number of side effects, and thus the search for new antimicrobial and antifungal agents is ...
O. P. Dolhikh, M. I. Romanenko, D. H. Ivanchenko, K. V. Aleksandrova, N. M. Polishchuk   +4 more
doaj   +1 more source

Vasoactive intestinal peptide prevents lung injury due to xanthine/xanthine oxidase

, 1990
Reactive oxygen species mediate injury and inflammation in many tissues. The addition of xanthine and xanthine oxidase to perfused rat lungs led to increases in peak airway pressure and perfusion pressure, pulmonary edema, and increased protein content ...
M. Trotz, H. Pakbaz, H. Foda, H. Sakakibara, H. Berisha, S. I. Said   +5 more
core   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Purification and characterization of mouse liver xanthine oxidase.

, 1990
Xanthine oxidase (EC 1.1.3.22) is purified to homogeneity from mouse liver after induction with bacterial lipopolysaccharide. The enzyme has an apparent molecular weight of 300,000 in its native state and it is suggested to be constituted of two ...
Ghezzi P, RACCHI, MARCO, Terao M, Garattini E., Carpani G   +4 more
core   +2 more sources

Beyond Removal Efficiency: Environmental Risk Assessment of Tartrazine Degradation via ZnO and TiO2 Nanoparticles in Mussels

Environmental Toxicology, EarlyView.
ABSTRACT Tartrazine (TZ) is a widely used synthetic azo dye with high aqueous stability, resulting in persistence in wastewater. Photoreactive nanomaterials, principally zinc oxide (ZnO) and titanium dioxide (TiO2) nanoparticles (NPs), are frequently employed for dye removal under light‐exposed conditions; nevertheless, their ecotoxicological ...
İrem Can, Ezgi Can Güzel, Volkan Saritunç, Selin Ertürk Gürkan   +3 more
wiley   +1 more source

Response of growth and formation of microtubers in potato plants to kinetin and coconut milk, and their content of the medicinally active compounds Lutein and Xanthine, in vitro.

Journal of Medicinal and Industrial Plant Sciences
This study was conducted to investigate the effect of kinetin and coconut milk on the formation of micro tubers in potato plants and their content of medically active compounds in vitro.
Lamiaa K. Al-Amery, Zainab J. Al-Mousawi, Ali Ali   +2 more
doaj   +1 more source

XDH Inhibits the Progression of Colorectal Cancer via Regulating Ferritinophagy Signaling. [PDF]

J Biochem Mol Toxicol
XDH inhibits the progression of CRC via mediating ferritinophagy and ferroptosis. Therefore, XDH/ferritinophagy may be a potential target for CRC. ABSTRACT Xanthine dehydrogenase (XDH) is involved in the progression of various cancer. This study aimed to investigate its potential in colorectal cancer (CRC). Gene expression was determined using RT‐qPCR,
Zhang H, Yan M, Li M, Gu J, Wang X, Ding J, Luo S.   +6 more
europepmc   +2 more sources

Investigation of the Protective Effect of Morin on Oxidative Stress and Apoptosis in Malathion‐Induced Hepatotoxicity in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Malathion (MAL) is a widely used organophosphate pesticide associated with hepatotoxicity through oxidative stress and apoptosis. Morin, a naturally occurring flavonoid, exhibits potent antioxidant and anti‐inflammatory properties. This study investigated oxidative stress, inflammatory, and apoptotic alterations induced by acute and subacute ...
Seval Yılmaz, Eda İ. Demirbağ, Hakan Bağ, Ali O. Çeribaşı   +3 more
wiley   +1 more source