Results 181 to 190 of about 16,447 (208)
Some of the next articles are maybe not open access.
Ethanol as a xanthine dehydrogenase inhibitor
Metabolism, 1995In the present study, we investigated whether ethanol inhibits the activity of xanthine dehydrogenase. Ethanol and/or inosine were administered to normal subjects, and plasma concentration and urinary excretion of purine bases were measured together with blood concentrations of lactic acid and pyruvic acid.
Tetsuya Yamamoto +4 more
openaire +2 more sources
Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia
American Journal of Physiology-Lung Cellular and Molecular Physiology, 1996The present study determined the effect of hypoxia on xanthine dehydrogenase (XDH) and xanthine oxidase (XO) activity and gene and protein expression in cultured bovine aortic endothelial cells (BAEC). BAEC were exposed to hypoxia (3% O2) or anoxia (0% O2) for 24 or 48 h and to 24 h of hypoxia followed by 24 h of reoxygenation.
T. P. Huecksteadt +4 more
openaire +3 more sources
Comparison of the kinetic behaviour of xanthine oxidase and xanthine dehydrogenase
Journal of Molecular Catalysis, 1981Abstract In the oxidation of hypoxanthine and xanthine by chicken liver xanthine dehydrogenase and bovine liver and milk xanthine oxidase, activation appears at high substrate concentrations. Hypoxanthine concentrations greater than 0.04 mM inhibit the bovine enzyme; concentrations greater than 0.09 mM inhibit the milk enzyme. On the other hand, uric
Jordi Galilea +2 more
openaire +2 more sources
Occurrence of xanthine dehydrogenase in Chlamydomonas reinhardii: A common cofactor shared by xanthine dehydrogenase and nitrate reductase [PDF]
Planta, 1981 Wild-type Chlamydomonas reinhardii cells have xanthine dehydrogenase activity when grown with nitrate, nitrite, urea, or amino acid media. Mutant strains 102, 104, and 307 of Chlamydomonas, lacking both xanthine dehydrogenase and nitrate reductase activities, were incapable of restoring the NADPH-nitrate reductase activity of the mutant nit-1 of ...
Emilio Fernández, Jacobo Cárdenas
openaire +2 more sources
The FEBS Journal, 2008
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Takeshi Nishino +4 more
openaire +3 more sources
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Takeshi Nishino +4 more
openaire +3 more sources
The relationship of phosphate and lipids to xanthine dehydrogenase
Experientia, 1968La xanthine deshydrogenase, enzyme du foie de rat, a ete obtenue par 2 procedes differents: (a) avec et (b) sans traitement par le Butanol. La teneur totale en phosphore des 2 preparations a ete etonnament elevee. Soixante %, a peu pres, du phosphore total s'est montre soluble dans des solvents de lipides.
Emilio Mitidieri, Ottilia R. Affonso
openaire +3 more sources
Liver xanthine dehydrogenase and iron mobilization
Biochemical and Biophysical Research Communications, 1982Abstract Administration of a tungsten-supplemented diet to young rats for 10 weeks resulted in an 80% – 90% reduction in the liver xanthine dehydrogenase activity and a 100% increase in the liver non-heme iron content as compared to control animals. A time course study of the effect of dietary tungsten in adult rats demonstrated that an increase in ...
Mark C. Walker +2 more
openaire +3 more sources
Inhibitory action of quercetin on xanthine oxidase and xanthine dehydrogenase activity
Pharmacological Research Communications, 1985Quercetin is an equally good inhibitor of xanthine oxidase (type O, oxygen-reducing enzyme) and xanthine dehydrogenase (type D, NAD+-reducing enzyme) activity of a preparation of the xanthine-oxidizing enzyme partially purified from rat liver. The inhibition seems competitive with the oxidase form and non-competitive (mixed-type) with the dehydrogenase
Marina Valente +2 more
openaire +3 more sources
Control of xanthine dehydrogenase in the chick pancreas
Developmental Biology, 1967Abstract Fisher et al. (1967) have shown that pancreatic xanthine dehydrogenase in newly hatched chicks is induced by feeding whereas this enzyme in the liver, kidney, and duodenum is unaffected by the ingestion of food. This induction is due to some substance(s) in the feed and not to the nutritional balance of the diet.
J.R. Fisher, W.D. Woodward
openaire +3 more sources
Xanthine dehydrogenase of chicken liver
Biochimica et Biophysica Acta, 1955Xanthine dehydrogenase of chicken liver is shown to reduce DPN nearly as fast as it reduces methylene blue. Strong evidence is produced showing that DPN is the in vivo acceptor for this enzyme and comparisons with milk xanthine oxidase are made. Other properties of the enzyme are described.
openaire +3 more sources