Triterpenes with 5-Lipoxigenase (5-LOX) and Xanthine Oxidase (XOD) Inhibitory Activity from the Stem of Ficus Aurantiaca Griff [PDF]
, 2013 Shukranul Mawa +2 more
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Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. [PDF]
, 2019 ObjectiveLesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI. The aim of the study was
Baumgartner, Scott +8 more
core +1 more source
Pyrogallol is a key component for xanthine oxidase inhibition by the leaves of Ammannia baecifera
, 2023 M. Rowshanul Habib +3 more
openalex +2 more sources
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Portal Hypertension &Cirrhosis, EarlyView.MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
Preparative Electrochemical Reduction of 2-Amino-6-chloropurine and Synthesis of 6-Deoxyacyclovir, a Fluorescent Substrate of Xanthine Oxidase and a Prodrug of Acyclovir. [PDF]
, 1987 J. T. Kuśmierek +4 more
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XANTHINE OXIDASE INHIBITORY PROPERTIES OF 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES
, 2021 Mihajlo Gajić +6 more
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SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications
Small, EarlyView.This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi +14 more
wiley +1 more source
Oxidative Stress Detection With Escherichia Coli Harboring A katG\u27::lux Fusion [PDF]
, 1996 A plasmid containing a transcriptional fusion of the Escherichia coli katG promoter to a truncated Vibrio fischeri lux operon (luxCDABE) was constructed. An E.
Belkin, S. +4 more
core +2 more sources
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
Environmental Toxicology, EarlyView.ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
Техника и технология пищевых производствPeptides offer a promising analogue to synthetic drugs in treating hyperuricemia. This article introduces reliable amino acid patterns that cause the inhibitory xanthine oxidase (CSR) activity of peptides.
Anastasia V. Smirnova +1 more
doaj +1 more source