Results 131 to 140 of about 300,913 (307)
Non‐canonical PKG1 regulation in cardiovascular health and disease
British Journal of Pharmacology, EarlyView.It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Attenuation of ischemic liver injury by prostaglandin E
, 1998 Background: Prostaglandin has been reported to have protective effects against liver injury. Use of this agent in clinical settings, however, is limited because of drugrelated side effects.
Ishizaki, N +8 more
core +1 more source
Molecules, 2018 Xanthine oxidase, an enzyme present in significant levels in the intestine and liver, metabolizes hypoxanthine to xanthine and xanthine to uric acid in the purine catabolic pathway. An inhibitory compound acting against xanthine oxidase was isolated from
Xiao-Xiao Liu +8 more
doaj +1 more source
The FEBS Journal, EarlyView.A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley +1 more source
International Journal of Molecular Sciences, 2011 Evaluation of abundantly available agro-industrial by-products for their bioactive compounds and biological activities is beneficial in particular for the food and pharmaceutical industries.
E. Oskoueian +3 more
semanticscholar +1 more source
Journal of Diabetes Investigation, EarlyView.High uric acid (UA) facilitates diabetes progression and is responsible for developing other diseases, such as cardiovascular disease and renal disease. Lifestyle modifications could lower UA levels, but relevant evidence is required in patients with type 2 diabetes.
Jie Li, Ertao Zhang, Zhao Dong, Yan Liu
wiley +1 more source
音響力学的治療におけるエピルビシン内包ミセルの機能に関する研究 [PDF]
, 2019 博士(医学) 甲第699号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Kazuhisa TAKEMAE・Jun OKAMOTO・Yuki HORISE・Ken MASAMUNE・Yoshihiro MURAGAKI，タイトル:Function of Epirubicin-Conjugated Polymeric Micelles in Sonodynamic Therapy，掲載誌:Frontiers in pharmacology(1663-9812)，巻・頁・年:10巻 p.546 ...
竹前 和久
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Xanthine Oxidases in Different Species.
Experimental Biology and Medicine, 1951 SummaryA study of the xanthine oxidases in selected tissue homogenates from different species showed that the enzymes present in bird tissues was a dehydrogenase rather than an oxidase, since the a...
Dan A. Richert, W. W. Westerfeld
openaire +2 more sources
Journal of applied physiology, 2011 Local cutaneous heating produces vasodilation that is largely nitric oxide (NO) dependent. We showed that angiotensin II (ANG II) attenuates this by an ANG II receptor, type 1 (AT1R)-dependent mechanism that is reversible with the antioxidant ascorbate ...
M. Medow +4 more
semanticscholar +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn +12 more
wiley +1 more source