Results 131 to 140 of about 299,059 (319)
High uric acid (UA) facilitates diabetes progression and is responsible for developing other diseases, such as cardiovascular disease and renal disease. Lifestyle modifications could lower UA levels, but relevant evidence is required in patients with type 2 diabetes.
Jie Li, Ertao Zhang, Zhao Dong, Yan Liu
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ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn+12 more
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Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi+4 more
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Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas+1 more
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Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra+9 more
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Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich+5 more
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Studies on xanthine oxidase [PDF]
David Ezra Green, Malcolm Dixon
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Oxidative stress is considered a central pathophysiological event in cardiovascular disease, including hypertension. Early age reduction in renal mass is associated with hypertension and oxidative stress in later life, which is aggravated by increased ...
Maria Peleli+6 more
doaj +1 more source
The role of xanthine oxidase in
Oxygen radicals have been proposed to be involved in the induction of liver cell damage during reperfusion after ischemia. The role of xanthine oxidase in this process and the potential of the antioxidant system have been studied in a model of in vivo ischemia of rat liver followed by 1 h reperfusion by the use of ...
Frederiks, W.M., Bosch, K.S.
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It is important to accurately measure enzyme activities in research studies to evaluate parameters, and many factors may affect the results of the measurements. The aim of this study was to investigate the effects of storage conditions (time and temperature) and different homogenisation buffers (PBS or KCl) on the measurement of SOD, CAT and ADA enzyme
Burcu Menekse Balkan+5 more
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