Results 61 to 70 of about 37,916 (254)

KHẢO SÁT KHẢ NĂNG ỨC CHẾ ENZYME XANTHINE OXIDASE TỪ LÁ SA KÊ (ARTOCARPUS ALTILIS (PARK.) FOSB)

Tạp chí Khoa học Đại học Cần Thơ, 2014
Tăng acid uric không chỉ là nguyên nhân gây nên bệnh gout, mà còn làm tăng nguy cơ bệnh tim mạch, sỏi thận, đái tháo đường và các hội chứng chuyển hóa.
Đái Thị Xuân Trang, Huỳnh Ngọc Trúc, Nguyễn Trọng Tuân   +2 more
doaj  

Inhibition of xanthine oxidase by flavonoids. [PDF]

Agricultural and Biological Chemistry, 1985
The influence of nineteen flavonoids on cow’s milk xanthine oxidase (xanthine: oxygen oxidoreductase, EC 1.2.3.2) was investigated. The enzyme activity was estimated by measuring the increase in absorbance at 290 nm due to uricate formation as well as by a colorimetric method assaying hydrogen peroxide generated from uricate by uricase.
Iio, Masayoshi, MORIYAMA, Ayako, MATSUMOTO, Yoshiko, TAKAKI, Nahoko, FUKUMOTO, Michi   +4 more
openaire   +2 more sources

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

BMC Chemistry, 2019
Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik, Priyanka Dhiman, Anurag Khatkar   +2 more
doaj   +1 more source

Antioxidant activity, xanthine oxidase inhibition and acute oral toxicity of Dillenia philippinensis Rolfe (Dilleniaceae) leaf extract. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2021
Context: Hyperuricemia is a metabolic syndrome characterized by a high serum uric acid level with an increased risk of gout, diabetes, cardiovascular and renal disease.
Sarah S. Ansari, Patricia H. Diño, Agnes L. Castillo, Librado A. Santiago   +3 more
doaj  

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

Summer Savory (Satureja hortensis) Extract Inhibits Xanthine Oxidase [PDF]

Journal of Medicinal Plants and By-products, 2015
Xanthine oxidase plays crucial roles in the production of reactive oxygen species (ROS), and uric acid in blood which may lead to gout, one of the oldest known forms of arthritis amongst humans.
Yeganeh Teimoori-Boghsani, Mohammad Bagher Bagherieh-Najjar, Manijeh Mianabadi, Majid Azim Mohseni   +3 more
doaj  

Optimization of the Extraction Conditions and Biological Evaluation of Dendropanax morbifera H. Lev as an Anti-Hyperuricemic Source

Molecules, 2018
Dendropanax morbifera H. Levis a medicinal plant native to South Korea, East Asia, and South America. Among some 75 species, one species grows in Korea. In previous studies, D.
Seung-Sik Cho, Seung-Hui Song, Chul-Yung Choi, Kyung Mok Park, Jung-Hyun Shim, Dae-Hun Park   +5 more
doaj   +1 more source

A Simulation Study of Inhibition Assay With Theophylline on the Enzymatic Hydrolysis of p‐Nitrophenyl Phosphate With Alkaline Phosphatase in a Continuous Mode of Electrophoretically Mediated Microanalysis

ELECTROPHORESIS, EarlyView.
Inhibition assays in in‐capillary continuous enzymatic reaction were simulated using a MATLAB matrix. The enzymatic hydrolysis of p‐nitrophenyl phosphate (S) with alkaline phosphatase (ALP) was adopted as a model enzymatic reaction, where theophylline (I) was used as a model inhibitor.
Toshio Takayanagi, Asuka Nomoto, Hitoshi Mizuguchi   +2 more
wiley   +1 more source

The Role of System-Specific Molecular Chaperones in the Maturation of Molybdoenzymes in Bacteria

Biochemistry Research International, 2011
Biogenesis of prokaryotic molybdoenzymes is a complex process with the final step representing the insertion of a matured molybdenum cofactor (Moco) into a folded apoenzyme.
Meina Neumann, Silke Leimkühler
doaj   +1 more source