Results 1 to 10 of about 5,102 (140)

Dose-Dependent Protective and Inductive Effects of Xanthohumol on Oxidative DNA Damage in Saccharomyces cerevisiae [PDF]

Food Technology and Biotechnology, 2016
The effect of xanthohumol, a prenylflavonoid isolated from the hop plant (Humulus lupulus L.), on Saccharomyces cerevisiae DNA oxidative damage and viability was evaluated. Yeast cultures under oxidative stress, induced by H2O2, displayed stronger growth
Daniel O. Carvalho, Rui Oliveira, Björn Johansson, Luís F. Guido   +3 more
doaj   +5 more sources

Deciphering a novel RP-HPLC based bioanalytical method for Estimation of xanthohumol in rat plasma and postbiotic-based nanostructured lipid carriers [PDF]

Scientific Reports
The study aimed to establish an accurate, specific, linear, precise, and robust method for quantifying xanthohumol loaded in nanostructured lipid carriers using the liquid chromatography.
Bushra Bashir, Monica Gulati, Sukriti Vishwas, M. V. N. L. Chaitanya, Sharfuddin Mohd, Vancha Harish, Gaurav Gupta, Nikhil B. Khandale, Surya Nath Pandey, Seung-Hyun Kim, Muthu Thiruvengadam, Sachin Kumar Singh   +11 more
doaj   +2 more sources

Proteomic antibacterial characterization of flavonoid xanthohumol and probiotic Clostridium butyricum on pathogenic Clostridioides difficile [PDF]

Chinese Medicine
Background The management of dysbiotic gut microbiota in Clostridioides difficile infection has attracted increasing scholarly attention. The development of therapeutic agents with low toxicity, derived from both the flavonoid xanthohumol and the short ...
Shenkun Wei, Guorong Li, Qiong Yang, Xinping Zhu, Junjie Liang, Mengyi Liu, Zijian Chen, Xia Liu, Jun-Yu Xu, Wei Chen   +9 more
doaj   +2 more sources

Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b [PDF]

Frontiers in Pharmacology
ContentDiabetic kidney disease (DKD), commonly termed diabetic nephropathy (DN), is characterized by oxidative stress and renal tubular epithelial cells apoptosis driven by high glucose (HG).ObjectiveTo explore the protective effects and underlying ...
Jian Hao, Hui Li, Weimin Yu
doaj   +2 more sources

Purification of Spent Hop Cone (Humulus lupulus L.) Extract with Xanthohumol Using Mesoporous Superparamagnetic Iron Oxide Nanoparticles [PDF]

Antioxidants
(1) Background: Over 90% of hop crops are currently used in beer production, with a small part used in the cosmetics and pharmaceutical industries. Spent hops as a waste product contain one of the strongest antioxidants, xanthohumol. The aim of the study
Natalia Żuk, Sylwia Pasieczna-Patkowska, Ewelina Grabias-Blicharz, Magdalena Pizoń, Jolanta Flieger   +4 more
doaj   +2 more sources

Effects of Natural Ingredient Xanthohumol on the Intestinal Microbiota, Metabolic Profiles and Disease Resistance to Streptococcus agalactiae in Tilapia Oreochromis niloticus [PDF]

Microorganisms
Streptococcus agalactiae (SA) is a severe prevalent pathogen, resulting in high morbidity and mortality in the global tilapia industry. With increasing bacterial resistance to antibiotics, alternative strategies are urgently needed.
Aiguo Huang, Yanqin Wei, Jialong Huang, Songlin Luo, Tingyu Wei, Jing Guo, Fali Zhang, Yinghui Wang   +7 more
doaj   +2 more sources

The Effect of Xanthohumol and Thymol on Candida albicans Filamentation and Its Impact on the Structure, Size, and Cell Viability of Biofilms Developed over Implant Surfaces [PDF]

Cells
The aim of this in vitro study was to evaluate the effect of xanthohumol and thymol on the impact of Candida albicans on the structure, size and cell viability of subgingival biofilms formed on dental implant surfaces. The structure and microbial biomass
Enrique Bravo, Marion Arce, David Herrera, Mariano Sanz   +3 more
doaj   +2 more sources

Reversing metabolic dysregulation in farnesoid X receptor knockout mice via gut microbiota modulation. [PDF]

PLoS ONE
The farnesoid X receptor (FXR), expressed in the liver and in the small intestine, is a key regulator of glucose and lipid metabolism. Its pharmacological modulation is explored as a potential treatment for obesity-related metabolic impairments.
Ines Leila Paraiso, Armando Alcázar Magaña, Alexandra Alexiev, Thomas J Sharpton, Claudia S Maier, Chrissa Kioussi, Jan F Stevens   +6 more
doaj   +2 more sources

Xanthohumol overcomes osimertinib resistance via governing ubiquitination-modulated Ets-1 turnover [PDF]

Cell Death Discovery
Non-small cell lung cancer (NSCLC) is a prevalent and fatal malignancy with a significant global impact. Recent advancements have introduced targeted therapies like tyrosine kinase inhibitors (TKIs) such as osimertinib, which have improved patient ...
Ying Ma, Ruirui Wang, Jinzhuang Liao, Pengfei Guo, Qiang Wang, Wei Li   +5 more
doaj   +2 more sources

Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice. [PDF]

PLoS ONE, 2012
BACKGROUND: Xanthohumol is expected to be a potent anti-atherosclerotic agent due to its inhibition of cholesteryl ester transfer protein (CETP). In this study, we hypothesized that xanthohumol prevents atherosclerosis in vivo and used CETP-transgenic ...
Hiroshi Hirata, Yimin, Shuichi Segawa, Moeko Ozaki, Naoyuki Kobayashi, Tatsuro Shigyo, Hitoshi Chiba   +6 more
doaj   +1 more source