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A Novel Look at Mechanisms and Applications of Xanthohumol (XN) in Dermatology and Cosmetology. [PDF]
Int J Mol SciKołodziejczak A +4 more
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Green Antimicrobials: Innovative Applications of Hops Extracts as Biocontrol Agents. [PDF]
PathogensPaniagua-García AI +2 more
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Recent Advances in the Synthesis and Biological Applications of Prenylated Chalcones. [PDF]
Int J Mol SciLaiche MH, Barlow JW.
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Total Synthesis of Xanthohumol
Journal of Natural Products, 2007The total synthesis of xanthohumol (1) was accomplished in 10% overall yield from phloracetophenone after six steps. Insertion of a prenyl group onto the aryl ring was achieved by a para-Claisen rearrangement after using a Mitsunobu reaction to establish the key prenyl ether precursor.
Rahul S, Khupse, Paul W, Erhardt
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Enrichment of xanthohumol in the brewing process
Molecular Nutrition & Food Research, 2005Xanthohumol (XN), a component of hops, is lost in significant quantities in the conventional brewing process. In commercial beers less than 0.2 mg XN/L are found. In order to increase the yield of XN in the brewing process, the parameters of XN recovery were studied. During wort boiling, XN is largely isomerised to isoxanthohumol.
Sascha, Wunderlich +2 more
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Xanthohumol metabolites in faeces of rats
Phytochemistry, 2004Xanthohumol (1), isolated from hop, was fed to rats in a dose of 1000 mg kg(-1) body weight. The faeces of the animals were collected after 24 and 48 h and analysed for metabolites of 1. Approximately 89% of the recovered flavonoid-compounds consisted of unchanged 1.
Nookandeh, A. +6 more
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Photochemical transformations of xanthohumol
Tetrahedron Letters, 2013Abstract A photoinduced procedure for the addition of simple alcohols to xanthohumol, the major prenylated flavonoid of hop plants, has been developed. The reaction is regioselective, simple, and occurs in one pot to afford two new β adducts of xanthohumol.
Jarosław Popłoński +2 more
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Pitfalls in cell culture work with xanthohumol.
Die Pharmazie, 2012Xanthohumol, the most abundant prenylated chalcone in hop (Humulus lupulus L.) cones, is well known to exert several promising pharmacological activities in vitro and in vivo. Among these, the chemopreventive, anti-inflammatory and anti-cancer effects are probably the most interesting.
Motyl, M., Kraus, B., Heilmann , J.
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