Results 171 to 180 of about 4,620 (190)

CXCL10/XCL1 fusokine elicits in vitro and in vivo chemotaxis

Biotechnology Letters, 2014
Fusokines are proteins formed by the fusion of two cytokines. They have greater bioavailability and therapeutic potential than individual cytokines or a combination of different cytokines. Interferon-gamma-inducible protein 10 (CXCL10) and lymphotactin (XCL1) are members of the chemotactic family of cytokines, which induce tumor regression by eliciting
Yessica E, Sanchez-Lugo, Jose J, Perez-Trujillo, Yolanda, Gutierrez-Puente, Aracely, Garcia-Garcia, Humberto, Rodriguez-Rocha, Oralia, Barboza-Quintana, Gerardo E, Muñoz-Maldonado, Odila, Saucedo-Cardenas, Roberto Montes, de Oca-Luna, Maria J, Loera-Arias   +9 more
openaire   +2 more sources

Genetic diversity of chemokine XCL1 and its receptor XCR1 in murine rodents

Developmental & Comparative Immunology, 2019
The chemokine ligand XCL1 plays critical roles in immune responses with diverse physiological and pathological implications through interactions with a cognate G protein-coupled receptor XCR1. To shed insight into their versatile nature, we analyzed genetic variations of XCL1 and XCR1 in murine rodents, including commonly-used model organisms Mus ...
Feifei, Xu, Dan, He, Ruihong, Ning, Bo, Zeng, Cody W, Thompson, Ying, Li, Dawei, Wang, Yan, Li   +7 more
openaire   +2 more sources

Intratumoral delivery of a highly active form of XCL1 enhances antitumor CTL responses through recruitment of CXCL9‐expressing conventional type‐1 dendritic cells

International Journal of Cancer
Conventional type 1 dendritic cells (cDC1s) play a crucial role in antitumor immunity through the induction and activation of tumor‐specific CD8+ cytotoxic T cells (CTLs).
Momo Kamei, K. Matsuo, Yusuke Yoshida, K. Shimada, M. Otsuki, Nao Fujimoto, Miho Ishibashi, Y. Quan, F. Kamiyama, Yuta Hara, Shiki Takamura, Takashi Nakayama   +11 more
semanticscholar   +1 more source

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in protection against West Nile virus within the CNS

Journal of Immunology, 2021
West Nile Virus (WNV) is a leading cause of mosquito-borne neuroinvasive disease in the US. Following infection, WNV can cause neuronal injury and disease.
D. Durrant, Alejandro Cortes, Marina O Alvarado   +2 more
semanticscholar   +1 more source

Abstract 6659: Oncolytic herpes simplex virus expressing XCL1 and FLT3L modulate the intratumoral immune response and improve the anti-tumor efficacy in a metastatic breast tumor model

Cancer Research
Patients with metastatic breast cancer (MBC) have a dismal prognosis, with a 5-year survival rate of only 26%. The inadequate infiltration of immune cells targeting the tumor microenvironment (TME) is a key factor contributing to this low survival rate.
Himanshu Soni, Liqun Gu, S. Roberge, Heena Kumra, Hiroshi Nakashima, E. Chiocca, Yves Boucher   +6 more
semanticscholar   +1 more source

Admission C-reactive protein, D-dimer, IL-6 and XCL1/lymphotactin levels as predictors of 28-day mortality in COVID-19 patients: a prospective cohort study

Bali Medical Journal
Link of Video Abstract: https://youtu.be/cQUhwa50jAM   Background: Predictors of mortality in COVID-19 patients, which are essential factors in guiding patient management, are poorly understood.
Adityo Susilo, H. Pohan, C. Rumende, Iris Rengganis, A. Harahap, A. Kekalih, D. Wulandari, I. SahBandar, S. Suwarto   +8 more
semanticscholar   +1 more source

Bacterial lipopolysaccharides stimulate production of XCL1, a calcium-dependent lipopolysaccharide-binding serum lectin, in Xenopus laevis

Developmental & Comparative Immunology, 2013
Xenopus laevis serum lectin XCL1 is a newly identified molecule of the XCGL (or X-lectin) family, a unique group of Ca(2+)-dependent lectins that have a fibrinogen-like domain. The XCL1 protein was purified from lipopolysaccharide (LPS)-stimulated frog sera by sequential affinity chromatography on heparin-acrylic beads and galactose-Sepharose.
Saburo, Nagata, Sayo, Nishiyama, Yumi, Ikazaki   +2 more
openaire   +2 more sources

Abstract A54: Laser-assisted intradermal delivery of Xcl1-specific fusion vaccines induces potent antitumor response

Cancer Immunology Research, 2015
Abstract Dendritic cells (DCs) are highly efficient specialized antigen-presenting cells and have been regarded as promising targets in cancer immunotherapy. Cross-presentation of antigen by a subset of DCs, the CD8α-type DCs to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors.
Dorothea Terhorst, Dorothea Terhorst, Even Fossum, Bjarne Bogen, Sandrine Henri, Bernard Malissen   +5 more
openaire   +1 more source

Regulating the anion disorder and synthesizing the low-cost and high-performance Li6-xPS5-xCl1+x solid electrolytes

Journal of Alloys and Compounds, 2023
Chengyu Mo, Yutao Yang, Zhenyu Wang, Yanpeng Lv, Rongzheng Tian, Zixiang Zhao, Hongzhou Zhang, Chunliang Li, Lianqi Zhang, Yongan Yang, Dawei Song   +10 more
semanticscholar   +1 more source

[Biological activity of purificated swine XCL1 protein and preparation of its polyclonal antibody].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2012
To obtain purificated his-XCL1 recombinant protein of porcine in vitro and prepare the associated polyclonal antibody; To study how the recombinant protein affects on lymphocytes proliferation.Purify the recombinant protein using HiTrap(TM); Chelating HP chromatographic column; Check the purified product using SDS-PAGE; Detect the expression of the ...
Yao-li, Wu, Jun-ge, Wen, Yan, Sun, De-li, Zhang   +3 more
openaire   +1 more source