Results 151 to 160 of about 4,678 (171)

Glycosylated recombinant human XCL1/lymphotactin exhibits enhanced biologic activity

Journal of Immunological Methods, 2005
Chemokines are a family of small, secreted chemoattractant cytokines that regulate distribution and function of leukocytes during immune responses. While most chemokines are members of the CC or CXC subgroups, XCL1, also known as lymphotactin, is the sole member of the C subgroup.
Annabelle Chua, Alan M Krensky, Carol Clayberger   +2 more
exaly   +3 more sources

Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice

Biochemical and Biophysical Research Communications, 2010
Understanding dendritic cell (DC) subset functions should lead to the development of novel types of vaccine. Here we characterized expression of XC chemokine receptor 1 (XCR1) and its ligand, XCL1. Murine XCR1 was the only chemokine receptor selectively expressed in CD8alpha(+) conventional DCs.
Katsuaki Hoshino, Tsuneyasu Kaisho, Hiroaki Hemmi   +2 more
exaly   +3 more sources

Genetic diversity of chemokine XCL1 and its receptor XCR1 in murine rodents

Developmental and Comparative Immunology, 2019
The chemokine ligand XCL1 plays critical roles in immune responses with diverse physiological and pathological implications through interactions with a cognate G protein-coupled receptor XCR1. To shed insight into their versatile nature, we analyzed genetic variations of XCL1 and XCR1 in murine rodents, including commonly-used model organisms Mus ...
Bo Zeng, Cody Thompson
exaly   +3 more sources

CXCL10/XCL1 fusokine elicits in vitro and in vivo chemotaxis

Biotechnology Letters, 2014
Fusokines are proteins formed by the fusion of two cytokines. They have greater bioavailability and therapeutic potential than individual cytokines or a combination of different cytokines. Interferon-gamma-inducible protein 10 (CXCL10) and lymphotactin (XCL1) are members of the chemotactic family of cytokines, which induce tumor regression by eliciting
Yessica E, Sanchez-Lugo, Jose J, Perez-Trujillo, Yolanda, Gutierrez-Puente, Aracely, Garcia-Garcia, Humberto, Rodriguez-Rocha, Oralia, Barboza-Quintana, Gerardo E, Muñoz-Maldonado, Odila, Saucedo-Cardenas, Roberto Montes, de Oca-Luna, Maria J, Loera-Arias   +9 more
openaire   +2 more sources

The Chemokines CXCL10 and XCL1 Recruit Human Annulus Fibrosus Cells

Spine, 2012
Human annulus fibrosus tissue and cells were analyzed for the presence of chemokine receptors and the migratory effect of selected chemokines.To investigate spontaneous repair mechanisms and underlying cell recruitment in response to annular tears and degenerative defects.Resorption of herniated disc tissue and the attempt to close annulus tears with ...
Aldemar A, Hegewald, Katja, Neumann, Gregor, Kalwitz, Undine, Freymann, Michaela, Endres, Kirsten, Schmieder, Christian, Kaps, Claudius, Thomé   +7 more
openaire   +2 more sources

The prognostic significance of serum XCL1 concentration in patients with acute lymphoblastic leukemia: a pilot study

Annals of Hematology, 2017
There is no information about XCL1 in patients with acute lymphoblastic leukemia (ALL). The objective of this study was to correlate the serum levels of XCL1 and survival in ALL patients. Only ALL patients older than 12 months were considered to participate.
Cesar Homero, Gutiérrez-Aguirre, Juan Antonio, Flores-Jiménez, Julio, Alatorre-Ricardo, Olga Graciela, Cantú-Rodríguez, Adrián, Rosas-Taraco, Rosario, Salazar-Riojas, José Carlos, Jaime-Pérez, Mónica, Sánchez-Cárdenas, Leslie, López-Silva, Azalia M, Martínez-Castilla, Mario Cesar, Salinas-Carmona, David, Gómez-Almaguer   +11 more
openaire   +2 more sources

The chemokine XCL1 functions as a pregnancy hormone to program offspring innate anxiety

Brain, Behavior, and Immunity
Elevated levels of cytokines in maternal circulation increase the offspring's risk for neuropsychiatric disease. Because of their low homeostatic levels, circulating maternal cytokines during normal pregnancies have not been considered to play a role in fetal brain development and offspring behavior.
Rosa J. Chen, Anika Nabila, Judit Gal Toth, Heidi Stuhlmann, Miklos Toth   +4 more
openaire   +2 more sources

[Biological activity of purificated swine XCL1 protein and preparation of its polyclonal antibody].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2012
To obtain purificated his-XCL1 recombinant protein of porcine in vitro and prepare the associated polyclonal antibody; To study how the recombinant protein affects on lymphocytes proliferation.Purify the recombinant protein using HiTrap(TM); Chelating HP chromatographic column; Check the purified product using SDS-PAGE; Detect the expression of the ...
Yao-li, Wu, Jun-ge, Wen, Yan, Sun, De-li, Zhang   +3 more
openaire   +1 more source

Chemokines: XCL1, XCL2 and CX3CL1

2022
openaire   +1 more source

Depressed Levels of XCL1 in Allergic Asthmatic Plasma

Journal of Allergy and Clinical Immunology, 2008
S.W. Berquist, K.C. Nadeau
openaire   +1 more source