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Genetic diversity of chemokine XCL1 and its receptor XCR1 in murine rodents

Developmental and Comparative Immunology, 2019
The chemokine ligand XCL1 plays critical roles in immune responses with diverse physiological and pathological implications through interactions with a cognate G protein-coupled receptor XCR1. To shed insight into their versatile nature, we analyzed genetic variations of XCL1 and XCR1 in murine rodents, including commonly-used model organisms Mus ...
Bo Zeng, Cody Thompson
exaly   +3 more sources

Struktur-Funktionsanalyse des Chemokins XCL1

2021
Einleitung Chemokine vermitteln die Interaktion von Immunzellen. Das Chemokin XCL1 wird von aktivierten CD8+ T-Zellen und NK-Zellen sezerniert und besitzt die für Chemokine typische Tertiärstruktur, bestehend aus einem N-Terminus, einem antiparallelen β-Faltblatt, einer α Helix und einem freien C-Terminus von etwa 20 Aminosäuren.
openaire   +1 more source

The Chemokines CXCL10 and XCL1 Recruit Human Annulus Fibrosus Cells

Spine, 2012
Human annulus fibrosus tissue and cells were analyzed for the presence of chemokine receptors and the migratory effect of selected chemokines.To investigate spontaneous repair mechanisms and underlying cell recruitment in response to annular tears and degenerative defects.Resorption of herniated disc tissue and the attempt to close annulus tears with ...
Aldemar A, Hegewald   +7 more
openaire   +2 more sources

The chemokine XCL1 functions as a pregnancy hormone to program offspring innate anxiety

Brain, Behavior, and Immunity
Elevated levels of cytokines in maternal circulation increase the offspring's risk for neuropsychiatric disease. Because of their low homeostatic levels, circulating maternal cytokines during normal pregnancies have not been considered to play a role in fetal brain development and offspring behavior.
Rosa J. Chen   +4 more
openaire   +2 more sources

[Biological activity of purificated swine XCL1 protein and preparation of its polyclonal antibody].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2012
To obtain purificated his-XCL1 recombinant protein of porcine in vitro and prepare the associated polyclonal antibody; To study how the recombinant protein affects on lymphocytes proliferation.Purify the recombinant protein using HiTrap(TM); Chelating HP chromatographic column; Check the purified product using SDS-PAGE; Detect the expression of the ...
Yao-li, Wu   +3 more
openaire   +1 more source

Depressed Levels of XCL1 in Allergic Asthmatic Plasma

Journal of Allergy and Clinical Immunology, 2008
S.W. Berquist, K.C. Nadeau
openaire   +1 more source

Involvement of the ERK/HIF-1α/EMT Pathway in XCL1-Induced Migration of MDA-MB-231 and SK-BR-3 Breast Cancer Cells

International Journal of Molecular Sciences, 2021
Jungsook Cho, Cho Jungsook
exaly  

Immunogenicity of the Xcl1-SARS-CoV-2 Spike Fusion DNA Vaccine for COVID-19

Vaccines, 2022
Ligong Chen   +2 more
exaly  

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