Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis
Lymphotactin-XCL1 is a chemokine produced mainly by activated CD8? T-cells and directs migration of CD4? and CD8? lymphocytes and natural killer (NK) cells. We expressed human lymphotactin (LTN) by the lactic-acid bacterium Lactococcus lactis. Biological
Saucedo-Cardenas +16 more
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T-cell-derived XCL1 Facilitates Their Interaction With XCR1+ DC's During WNV Encephalitis [PDF]
West Nile virus (WNV), a mosquito-borne flavivirus, is the leading cause of arboviral- induced encephalitis in the United States. While most infections are asymptomatic, some patients develop symptoms that range from febrile illness to more severe ...
Kristen De La Torre
core
SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8<sup>+</sup> T cell immunity against bulky tumors via an IFN-I/NK/DC axis. [PDF]
Luo R +25 more
europepmc +1 more source
Combination of exosome vaccines, lenvatinib, and anti-PD-1 eradicates tumor in autochthonous hepatocellular carcinoma mice. [PDF]
Zuo B +11 more
europepmc +1 more source
Dietary sulfur amino acids enhance anti-tumor immunity in colon cancer via an NKT cell-XCL1-cDC1 circuit. [PDF]
Lobel L +26 more
europepmc +1 more source
A cDC1-NK/T-Malignant Cell Circuit Drives Immunogenic Remodeling Under PD-1 Blockade in Gastric Cancer. [PDF]
Nakatsuru T +24 more
europepmc +1 more source
Multi-omics analysis reveals MICB promotes cerebral atherosclerosis through FTMT suppression in NK and plasma cells. [PDF]
Dai Y +5 more
europepmc +1 more source
Efficacy and immunomodulatory effect of Claudin18.2-specific IL-7/XCL1 armored CAR-T cells in digestive tract cancer: preclinical and clinical analysis. [PDF]
Zhao X +16 more
europepmc +1 more source
Immune-mediated tumor regression and subsequent escape driven by antigen loss and major histocompatibility complex (MHC) class I downregulation following GPC3 DNA vaccination in hepatocellular carcinoma. [PDF]
Li H +6 more
europepmc +1 more source
Divergent cytotoxic and inflammatory functions of intratumoral Vδ2<sup>+</sup> γδ T cells in renal cell carcinoma. [PDF]
Oh WJ +6 more
europepmc +1 more source

