Results 101 to 110 of about 6,545 (188)
ABSTRACT The integrity of the pancreatic islet microvasculature is critical for endocrine function, yet it is progressively compromised by glucotoxicity in diabetes. While matrix metalloproteinases are implicated, the role of stromelysin‐1 as a potential upstream driver of endothelial dysfunction remains poorly defined.
Bing Wang +9 more
wiley +1 more source
EBI3 regulates the NK cell response to mouse cytomegalovirus infection [PDF]
Natural killer (NK) cells are key mediators in the control of cytomegalovirus infection. Here, we show that Epstein-Barr virus-induced 3 (EBI3) is expressed by human NK cells after NKG2D or IL-12 plus IL-18 stimulation and by mouse NK cells during mouse ...
Campbell +9 more
core +1 more source
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz +7 more
wiley +1 more source
Inductive pattern-based land use/cover change models: A comparison of four software packages [PDF]
International audienceLand use/cover change (LUCC), as an important factor in global change, is a topic that has recently received considerable attention in the prospective modeling domain.
Camacho Olmedo, Maria Teresa +4 more
core +4 more sources
Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu +4 more
wiley +1 more source
The transcriptional landscape of αβ T cell differentiation [PDF]
αβT cell differentiation from thymic precursors is a complex process, explored here with the breadth of ImmGen expression datasets, analyzing how differentiation of thymic precursors gives rise to transcriptomes. After surprisingly gradual changes though
Bendall, Sean +12 more
core +1 more source
A novel myeloid cell in murine spleen defined through gene profiling [PDF]
A novel myeloid antigen presenting cell can be generated through in vitro haematopoiesis in long-term splenic stromal cocultures. The in vivo equivalent subset was recently identified as phenotypically and functionally distinct from the spleen subsets of
Dabiri GA +5 more
core +1 more source
BackgroundDecidual natural killer (dNK) cells constitute approximately 70% of first-trimester decidual leukocytes and play critical roles in immune tolerance, angiogenesis, and trophoblast invasion.
Lidan Liu +4 more
doaj +1 more source
Zerobrane Matrix Mechanics, Monopoles and Membrane Approach in QCD
We conjecture that a T-dual form of pure QCD describes dynamics of point-like monopoles. T-duality transforms the QCD Lagrangian into a matrix quantum mechanics of zerobranes which we identify with monopoles.
Abrikosov A. +7 more
core +1 more source
Dendritic Cell Subtypes from Lymph Nodes and Blood Show Contrasted Gene Expression Programs upon Bluetongue Virus Infection [PDF]
Chantier qualité GAHuman and animal hemorrhagic viruses initially target dendritic cells (DCs). It has been proposed, but not documented, that both plasmacytoid DCs (pDCs) and conventional DCs (cDCs) may participate in the cytokine storm encountered in ...
Baranek T +43 more
core +4 more sources

