Results 101 to 110 of about 6,545 (188)

Consequences of CRISPR‐Cas9‐Mediated Stromelysin‐1 Knockout in Pancreatic Islet Microvascular Endothelial Cells

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT The integrity of the pancreatic islet microvasculature is critical for endocrine function, yet it is progressively compromised by glucotoxicity in diabetes. While matrix metalloproteinases are implicated, the role of stromelysin‐1 as a potential upstream driver of endothelial dysfunction remains poorly defined.
Bing Wang   +9 more
wiley   +1 more source

EBI3 regulates the NK cell response to mouse cytomegalovirus infection [PDF]

open access: yes, 2017
Natural killer (NK) cells are key mediators in the control of cytomegalovirus infection. Here, we show that Epstein-Barr virus-induced 3 (EBI3) is expressed by human NK cells after NKG2D or IL-12 plus IL-18 stimulation and by mouse NK cells during mouse ...
Campbell   +9 more
core   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

open access: yesAdvanced Functional Materials, Volume 36, Issue 12, 9 February 2026.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz   +7 more
wiley   +1 more source

Inductive pattern-based land use/cover change models: A comparison of four software packages [PDF]

open access: yes, 2014
International audienceLand use/cover change (LUCC), as an important factor in global change, is a topic that has recently received considerable attention in the prospective modeling domain.
Camacho Olmedo, Maria Teresa   +4 more
core   +4 more sources

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu   +4 more
wiley   +1 more source

The transcriptional landscape of αβ T cell differentiation [PDF]

open access: yes, 2014
αβT cell differentiation from thymic precursors is a complex process, explored here with the breadth of ImmGen expression datasets, analyzing how differentiation of thymic precursors gives rise to transcriptomes. After surprisingly gradual changes though
Bendall, Sean   +12 more
core   +1 more source

A novel myeloid cell in murine spleen defined through gene profiling [PDF]

open access: yes, 2019
A novel myeloid antigen presenting cell can be generated through in vitro haematopoiesis in long-term splenic stromal cocultures. The in vivo equivalent subset was recently identified as phenotypically and functionally distinct from the spleen subsets of
Dabiri GA   +5 more
core   +1 more source

dNK3 cells in normal pregnancy and recurrent pregnancy loss: from molecular identity to functional imbalance

open access: yesFrontiers in Immunology
BackgroundDecidual natural killer (dNK) cells constitute approximately 70% of first-trimester decidual leukocytes and play critical roles in immune tolerance, angiogenesis, and trophoblast invasion.
Lidan Liu   +4 more
doaj   +1 more source

Zerobrane Matrix Mechanics, Monopoles and Membrane Approach in QCD

open access: yes, 1999
We conjecture that a T-dual form of pure QCD describes dynamics of point-like monopoles. T-duality transforms the QCD Lagrangian into a matrix quantum mechanics of zerobranes which we identify with monopoles.
Abrikosov A.   +7 more
core   +1 more source

Dendritic Cell Subtypes from Lymph Nodes and Blood Show Contrasted Gene Expression Programs upon Bluetongue Virus Infection [PDF]

open access: yes, 2013
Chantier qualité GAHuman and animal hemorrhagic viruses initially target dendritic cells (DCs). It has been proposed, but not documented, that both plasmacytoid DCs (pDCs) and conventional DCs (cDCs) may participate in the cytokine storm encountered in ...
Baranek T   +43 more
core   +4 more sources

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