Results 81 to 90 of about 4,834 (170)

Machine Learning Interatomic Potentials for Energy Materials: Architectures, Training Strategies, and Applications

Advanced Energy Materials, Volume 16, Issue 39, 21 October 2026.
Machine learning interatomic potentials bridge quantum accuracy and computational efficiency for materials discovery. Architectures from Gaussian process regression to equivariant graph neural networks, training strategies including active learning and foundation models, and applications in solid‐state electrolytes, batteries, electrocatalysts ...
In Kee Park, Saeed Pourasad, Jinhong Mun, Arunkumar Chitteth Rajan, Tae Hyeon Park, Anand Rohit, Mohammad Zafari, Tan‐Lien Pham, Eunjae Jung, Bonseung Koo, Miran Ha, Gi Beom Sim, Hyun Gyu Park, Won Woong Choi, Kwanghyeon Jo, Soohaeng Yoo Willow, David ChangMo Yang, Chang Woo Myung, Geunsik Lee, Kwang S. Kim   +19 more
wiley   +1 more source

Spatiotemporal transcriptomics for tumour microenvironment remodelling in cancer progression and therapy

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review summarises how spatial transcriptomics technologies reveal tumour microenvironment heterogeneity and support the inference of dynamic remodelling during cancer progression. Abstract Background Spatiotemporal transcriptomics (STT) integrates spatially resolved gene expression with temporal information derived from staged samples, paired ...
Ying Kang, Qinjing Wang, Siqi Xu, Jiming Guo, Yue Ming, Weixing Chen, Min Wang, Zhijie Huang, Yisheng Huang, Bo Jia   +9 more
wiley   +1 more source

Primary human CD8+ T cells secrete XCL1.

, 2013
CD8+ T cells were activated with three different stimuli for 3 days: PMA plus ionomycin, anti-CD3/CD28 loaded beads, or PHA. Cells were washed and culture supernatants were harvested after 5 and 7 days to quantify XCL1 secretion.
Christina Guzzo (305744), Jamie Fox (502456), Raffaello Cimbro (172335), Paolo Lusso (172366), Huiyi Miao (172330), Anthony S. Fauci (73431), Yin Lin (421396), Brian F. Volkman (502457)   +7 more
core   +1 more source

Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site

, 2019
Fusing antigens to chemokines to target antigen presenting cells (APC) is a promising method for enhancing immunogenicity of DNA vaccines. However, it is unclear how different chemokines compare in terms of immune potentiating effects.
Tesfaye, Demo Yemane, Bogen, Bjarne, Braathen, Ranveig, Lysén, Anna Karin Christina, Gudjonsson, Arnar, Fossum, Even   +5 more
core   +1 more source

Prognostic Implications of Heterogeneity in Intra-tumoral Immune Composition for Recurrence in Early Stage Lung Cancer

Frontiers in Immunology, 2018
Background: Studies in the past have identified selected immune cells that associate with different clinical outcomes in non-small cell lung cancer (NSCLC).
Jyothi Thyagabhavan Mony, Matthew J. Schuchert   +1 more
doaj   +1 more source

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

MedComm, Volume 7, Issue 10, October 2026.
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo, Yizhao Xie, Rui Song, Mengdi Yang, Zhen Lin, Chao Guan, Zechen Wang, Jin Wen, Guang‐Liang Chen   +8 more
wiley   +1 more source

The herpesvirus 8 encoded chemokines vCCL2 (vMIP-II) and vCCL3 (vMIP-III) target the human but not the murine lymphotactin receptor

Virology Journal, 2008
Background Large DNA-viruses such as herpesvirus and poxvirus encode proteins that target and exploit the chemokine system of their host. The Kaposi sarcoma- associated herpes virus (KSHV) encodes three chemokines.
Lüttichau Hans R
doaj   +1 more source

Evasins: Biology and Therapeutic Potential of Broad‐Spectrum Chemokine Inhibitors

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Emilia L. Bialek, Roos Buds, Ingrid Dijkgraaf, Pedro E. Marques   +3 more
wiley   +1 more source

Chemotactic migration of cattle XCR1⁺ DC by mouse XCL1 and human XCL1.

, 2017
(A) The relative expression of cattle XCR1 mRNA from input cells (CD26+ DCs) in upper chamber and migrated cells (XCR1+ DC) in lower chamber. Difference in XCR1 expression between the two populations was calculated using one-tailed nonparametric t-test ...
Xueqing Ma (3687436), Yingli Chen (383063), Zengjun Lu (313655), Huifang Bao (2221972), Xingwen Bai (313652), Zaixin Liu (313659), Yuanfang Fu (2221978), Dong Li (212687), Pinghua Li (173201), Pu Sun (313657), Guoyan Wei (3700651), Yimei Cao (313653), Jing Zhang (23775), Kun Li (277035)   +13 more
core   +1 more source

Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant Semliki Forest Virus-derived vectors fosters dendritic cell-mediated T cell cross-priming [PDF]

, 2018
Multiple lines of evidence indicate a critical role for antigen cross-presentation by conventional BATF3-dependent type 1 classical dendritic cells (cDC1) in CD8-mediated antitumor immunity.
Azpilikueta, A, Melero, I, Rodriguez-Ruiz, ME, Smerdou, C, Sancho, D, Teijeira, A, Quezada, SA, Sanchez-Arraez, A, Casares, N, Berraondo, P, Sanchez-Paulete, AR, Ballesteros-Briones, MC, Etxeberria, I, Bolaños, E, Quetglas, JI, Labiano, S   +15 more
core   +3 more sources