Results 81 to 90 of about 4,678 (171)
Frontiers in Immunology, 2018 Background: Studies in the past have identified selected immune cells that associate with different clinical outcomes in non-small cell lung cancer (NSCLC).
Jyothi Thyagabhavan Mony +1 more
doaj +1 more source
Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley +1 more source
The inhibitory structure of XCL1 against HIV-1 is the all-β, alternatively-folded conformation.
, 2013 Dose-dependent inhibition of an XCL1-sensitive primary HIV-1 isolate (92HT599; X4/R5) by recombinant wild type (WT) XCL1 (green bars), and two stabilized structural variants: W55D, a variant preferentially adopting the all-β/alternatively-folded ...
Christina Guzzo (305744) +7 more
core +1 more source
Virology Journal, 2008 Background Large DNA-viruses such as herpesvirus and poxvirus encode proteins that target and exploit the chemokine system of their host. The Kaposi sarcoma- associated herpes virus (KSHV) encodes three chemokines.
Lüttichau Hans R
doaj +1 more source
Advanced Energy Materials, Volume 16, Issue 26, 8 July 2026.Silicon anodes in sulfide SSBs face coupled electrochemo‐mechanical failure by interface instability. This review examined recent advances and proposed mitigation strategies via material‐, electrode/interface‐, and cell‐level‐ engineering. We further evaluate scalable synthesis of sulfide SEs.
Murugesan Karuppaiah +4 more
wiley +1 more source
, 2020 Chemokine–receptor interactions play multiple roles in cancer progression. It was reported that the overexpression of X-C motif chemokine receptor 1 (XCR1), a specific receptor for chemokine X-C motif chemokine ligand 1 (XCL1), stimulates the ...
Ha Thi Thu Do, Jungsook Cho
core +1 more source
XCL1 inhibits HIV-1 infection irrespective of coreceptor usage.
, 2013 (A) Dose-dependent inhibition of prototypic X4 (magenta) and R5 (blue) HIV-1 strains (IIIB and BaL) by recombinant XCL1 (Peprotech) in PBMC. Virus replication was assessed by measuring the amount of p24 Gag antigen in culture supernatants via AlphaLISA ...
Christina Guzzo (305744) +7 more
core +1 more source
Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant Semliki Forest Virus-derived vectors fosters dendritic cell-mediated T cell cross-priming [PDF]
, 2018 Multiple lines of evidence indicate a critical role for antigen cross-presentation by conventional BATF3-dependent type 1 classical dendritic cells (cDC1) in CD8-mediated antitumor immunity.
Azpilikueta, A +15 more
core +4 more sources
Journal for ImmunoTherapy of CancerBackground Therapeutic efficacy of carcinoembryonic antigen (CEA)-specific chimeric antigen receptor (CAR) T cells against colorectal cancer (CRC) remains limited due to the unique characteristics and distinct microenvironments of tumor tissues.
Kun Chen +10 more
doaj +1 more source
, 2019 Fusing antigens to chemokines to target antigen presenting cells (APC) is a promising method for enhancing immunogenicity of DNA vaccines. However, it is unclear how different chemokines compare in terms of immune potentiating effects.
Tesfaye, Demo Yemane +5 more
core +1 more source