Results 71 to 80 of about 4,834 (170)
MedComm, Volume 7, Issue 11, November 2026.A Pan‐HEpatic single‐cell Atlas of T cells (Pheat) was constructed covering chronic hepatitis, cirrhosis, hepatocellular carcinoma (HCC), and healthy controls. CD8+ exhausted T cells (Tex) and CD4+ regulatory T cells (Treg) were delineated profound through decoding molecular and cellular variance, immune checkpoint networks, pathway analysis, and drug ...
Si‐Yuan Chen +18 more
wiley +1 more source
XCL1 Enhances Regulatory Activities of CD4+CD25highCD127low/− T Cells in Human Allergic Asthma [PDF]
The Journal of Immunology, 2008 Abstract Chemokine-mediated recruitment of regulatory cell subsets to the airway during inflammation and enhancement of their activities are potential strategies for therapeutic development in allergic asthma (AA). In this study, we aim to explore the role of XCL1, a chemokine associated with immune suppression and allergy, on CD4 ...
Khoa D, Nguyen +5 more
openaire +2 more sources
The inhibitory structure of XCL1 against HIV-1 is the all-β, alternatively-folded conformation.
, 2013 Dose-dependent inhibition of an XCL1-sensitive primary HIV-1 isolate (92HT599; X4/R5) by recombinant wild type (WT) XCL1 (green bars), and two stabilized structural variants: W55D, a variant preferentially adopting the all-β/alternatively-folded ...
Christina Guzzo (305744) +7 more
core +1 more source
Zhongguo aizheng zazhi, 2014 Background and purpose: More than 90% of cancer patients are incurable because of drug resistance. Activation of PI3K/Akt/mTOR signaling pathway in breast cancer, as a target for chemotherapy drugs has become a hot topic of breast cancer treatment.
白玉盘, 杨小利, 欧周罗
doaj
Interfacial Failure and Self‐Healing in Solid‐State Batteries
Advanced Materials, Volume 38, Issue 58, 16 October 2026.Dynamic interfacial self‐healing offers an adaptive route to mitigate coupled mechanical, chemical, and electrochemical degradation in solid‐state batteries. This review connects evolving interfacial failure mechanisms with physical‐flow, chemical‐restoration, stimuli‐responsive, and electric‐field‐assisted repair strategies, highlighting targeted self‐
Xinxin Zhu +8 more
wiley +1 more source
Advanced Science, Volume 13, Issue 57, 14 October 2026.ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang +9 more
wiley +1 more source
Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1 [PDF]
Journal of Virology, 2015 ABSTRACT HIV-1 replication is regulated in vivo by a complex network of cytokines and chemokines. XCL1/lymphotactin, a unique metamorphic chemokine, was recently identified as a broad-spectrum endogenous HIV-1 inhibitor that blocks viral entry via direct interaction with the gp120 envelope glycoprotein ...
Christina, Guzzo +4 more
openaire +2 more sources
XCL1 does not interact with or inhibit VSV-G-pseudotyped virus.
, 2013 (A) Virion capture was performed using anti-mouse immunomagnetic beads (M-Beads) armed with anti-VSV-G mAb (Anti-VSV) or anti-rabbit immunomagnetic beads (R-Beads) armed with XCL1 WT (XCL1). Equal amounts of VSV-G-pseudotyped virus were added to all bead
Christina Guzzo (305744) +7 more
core +1 more source
, 2020 Chemokine–receptor interactions play multiple roles in cancer progression. It was reported that the overexpression of X-C motif chemokine receptor 1 (XCR1), a specific receptor for chemokine X-C motif chemokine ligand 1 (XCL1), stimulates the ...
Ha Thi Thu Do, Jungsook Cho
core +1 more source
Advanced Science, Volume 13, Issue 57, 14 October 2026.Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger +8 more
wiley +1 more source