Results 121 to 130 of about 6,545 (188)

XCL1: a multifunctional chemokine with metamorphic properties and therapeutic potential after injury to the nervous system – review

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research
XC Motif Chemokine Ligand 1 (XCL1, known as lymphotactin), acting via XCR1, is a member of the chemokine family which includes molecules with chemotactic functions. However, subsequent years of research on this chemokine, while simultaneously exploring and understanding the complexity of the processes taking place in living organisms, have revealed a ...
Agata, Ciechanowska, Joanna, Mika
openaire   +2 more sources

IL-11/IL-11R signal inhibition by 9MW3811 remodels immune tumor microenvironment and enhances anti-tumor efficacy of PD-1 blockade

open access: yesnpj Precision Oncology
Recent studies have uncovered evidences for pro-tumorigenic activities attributed to IL-11, prompting a renewed focus on therapeutic strategies targeting IL-11 signaling for anti-tumor treatment. Here, we introduce 9MW3811, a monoclonal antibody designed
Chang Zhang   +8 more
doaj   +1 more source

Single-cell transcriptomics unveil profiles and interplay of immune subsets in rare autoimmune childhood Sjögren’s disease

open access: yesCommunications Biology
Childhood Sjögren’s disease represents critically unmet medical needs due to a complete lack of immunological and molecular characterizations. This study presents key immune cell subsets and their interactions in the periphery in childhood Sjögren’s ...
Myung-Chul Kim   +11 more
doaj   +1 more source

The Role of Chemokines in Obesity and Exercise-Induced Weight Loss

open access: yesBiomolecules
Obesity is a global health crisis that is closely interrelated to many chronic diseases, such as cardiovascular disease and diabetes. This review provides an in-depth analysis of specific chemokines involved in the development of obesity, including C-C ...
Wenbi He   +4 more
doaj   +1 more source

Progress in research on C-chemokine XCL1

open access: yesWorld Chinese Journal of Digestology, 2017
Lei Yu, Gui-Bo Yang
openaire   +1 more source

Efficacy and immunomodulatory effect of Claudin18.2-specific IL-7/XCL1 armored CAR-T cells in digestive tract cancer: preclinical and clinical analysis. [PDF]

open access: yesSignal Transduct Target Ther
Zhao X   +16 more
europepmc   +1 more source

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