Results 41 to 50 of about 41,389 (199)

Tuberculosis in prisons in sub-Saharan Africa--a potential time bomb. [PDF]

, 2011
No ...
Bates, Matthew, Kapata, Nathan, Mwaba, Peter, O'Grady, Justin, Zumla, Alimuddin   +4 more
core   +1 more source

Spatial heterogeneity of extensively drug resistant-tuberculosis in Western Cape Province, South Africa

Scientific Reports, 2022
Tuberculosis (TB) remains a leading infectious disease killer globally. Treatment outcomes are especially poor among people with extensively drug-resistant (XDR) TB, until recently defined as rifampicin-resistant (RR) TB with resistance to an ...
Karla Therese L. Sy, Sarah V. Leavitt, Margaretha de Vos, Tania Dolby, Jacob Bor, C. Robert Horsburgh, Robin M. Warren, Elizabeth M. Streicher, Helen E. Jenkins, Karen R. Jacobson   +9 more
doaj   +1 more source

A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]

, 2017
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A, Catanzaro, D, Fink, L, Jackson, RL, Pettigrove, M, Ramirez-Busby, SM, Rodwell, TC, Valafar, F   +7 more
core   +1 more source

Early access to bedaquiline for extensively drug-resistant (XDR) and pre-XDR tuberculosis [PDF]

European Respiratory Journal, 2019
This letter presents final safety and efficacy data from an early-access study of bedaquiline for treating (pre-)XDR-TBhttp://bit.ly ...
Irina Vasilyeva, Andrei Mariandyshev, Boris Kazennyy, Edita Davidavičienė, Nacer Lounis, Sofia Keim   +5 more
openaire   +1 more source

Drug-Resistant Tuberculosis--Current Dilemmas, Unanswered Questions, Challenges and Priority Needs [PDF]

, 2012
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim, Atun, Rifat, Chakaya, Jeremiah, Cox, Helen, Ditiu, Lucica, Ford, Nathan, Grobusch, Martin, Hoelscher, Michael, Lawn, Stephen D., Maeurer, Markus, Marais, Ben, Mchugh, Timothy D., McNerney, Ruth, Memish, Ziad, Migliori, Giovanni-Battista, Mwaba, Peter, O'Grady, Justin, Pletschette, Michel, Ramsay, Andrew, Raviglione, Mario, Schito, Marco, Squire, S. Bertel, Swaminathan, Soumya, Zumla, Alimuddin   +23 more
core   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Carbapenemase Producers Among Extensive Drug-Resistant Gram-Negative Pathogens Recovered from Febrile Neutrophilic Patients in Egypt

Infection and Drug Resistance, 2020
Samar S Mabrouk,1 Ghada R Abdellatif,1 Mona R El-Ansary,2 Khaled M Aboshanab,3 Yasser M Ragab4 1Department of Microbiology, Faculty of Pharmacy, Ahram Canadian University (ACU), 6th of October, Giza, Egypt; 2Department of Biochemistry, Modern University ...
Mabrouk S, Abdellatif G, El-Ansary M, Aboshanab K, Ragab Y   +4 more
doaj  

Morbidity and Mortality Associated with Typhoid Fever Among Hospitalized Patients in Hyderabad District, Pakistan, 2017-2018: Retrospective Record Review

JMIR Public Health and Surveillance, 2021
BackgroundHyderabad, Pakistan, was the first city to witness an outbreak of extensively drug resistant (XDR) typhoid fever. The outbreak strain is resistant to ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, fluoroquinolones, and third ...
Fatima, Munaza, Kumar, Santosh, Hussain, Mudassar, Memon, Naveed Masood, Vighio, Anum, Syed, Muhammad Asif, Chaudhry, Ambreen, Hussain, Zakir, Baig, Zeeshan Iqbal, Baig, Mirza Amir, Asghar, Rana Jawad, Ikram, Aamer, Khader, Yousef   +12 more
doaj   +1 more source

Molecular properties of (U)LIRGs: CO, HCN, HNC and HCO+

, 2007
The observed molecular properties of a sample of FIR-luminous and OH megamaser (OH-MM) galaxies have been investigated. The ratio of high and low-density tracer lines is found to be determined by the progression of the star formation in the system.
A. F. Loenen, Baan, Loenen, M. Spaans, Meijerink, Meijerink, Schilke, W. A. Baan   +7 more
core   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source