Results 11 to 20 of about 214,432 (171)

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa. [PDF]

PLoS ONE, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Borna Müller, Violet N Chihota, Manormoney Pillay, Marisa Klopper, Elizabeth M Streicher, Gerrit Coetzee, Andre Trollip, Cindy Hayes, Marlein E Bosman, Nicolaas C Gey van Pittius, Thomas C Victor, Sebastien Gagneux, Paul D van Helden, Robin M Warren   +13 more
doaj   +3 more sources

Prevalence of Pre-Extensively Drug-Resistant Tuberculosis (Pre XDR-TB) and Extensively Drug-Resistant Tuberculosis (XDR-TB) among Pulmonary Multidrug Resistant Tuberculosis (MDR-TB) at a Tertiary Care Center in Mumbai [PDF]

Journal of Krishna Institute of Medical Sciences University, 2016
Background: India is a high burden country for Tuberculosis (TB). As per the World Health Organization (WHO) statistics, 24000 cases of Multi Drug Resistant (MDR) TB were diagnosed in India in 2014.
Unnati D. Desai , Jyotsna M. Joshi
doaj   +2 more sources

Profile and risk factors of pre-XDR-TB and XDR-TB patients in a national reference hospital for Sumatra region of Indonesia. [PDF]

Narra J, 2023
The low treatment rate, low treatment success rate and high mortality rate of patients with pre-extensively drug-resistant tuberculosis (pre-XDR-TB) and extensively drug-resistant TB (XDR-TB) need serious attention.
Sinulingga HE, Sinaga BY, Siagian P, Ashar T.   +3 more
europepmc   +2 more sources

Epidemiology of extensively drug-resistant tuberculosis among patients with multidrug-resistant tuberculosis: A systematic review and meta-analysis

International Journal of Infectious Diseases, 2023
Objectives: To estimate the pooled proportion of extensively drug-resistant tuberculosis (XDR-TB) and pre-extensively drug-resistant tuberculosis (pre-XDR-TB) in patients with multidrug-resistant TB (MDR-TB).
Getu Diriba, Ayinalem Alemu, Bazezew Yenew, Habteyes Hailu Tola, Dinka Fikadu Gamtesa, Hilina Mollalign, Kirubel Eshetu, Shewki Moga, Saro Abdella, Getachew Tollera, Abebaw Kebede, Mesay Hailu Dangisso   +11 more
doaj   +1 more source

Frequency of first and second-line drug resistance-associated mutations among resistant Mycobacterium tuberculosis clinical isolates from São Paulo, Brazil [PDF]

Memorias do Instituto Oswaldo Cruz, 2020
BACKGROUND Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the number of new cases of multidrug resistant TB (MDR-TB), pre extensively drug-resistant TB (pre-XDR-TB) and extensively drug-resistant TB ...
Tania Matsui, Juliana Maíra Watanabe Pinhata, Michelle Christiane da Silva Rabello, Angela Pires Brandão, Lucilaine Ferrazoli, Sylvia Cardoso Leão, Cristina Viana-Niero, Rosangela Siqueira de Oliveira   +7 more
doaj   +1 more source

Yield of Systematic Longitudinal Screening of Household Contacts of Pre-Extensively Drug Resistant (PreXDR) and Extensively Drug Resistant (XDR) Tuberculosis Patients in Mumbai, India

Tropical Medicine and Infectious Disease, 2020
While risk of tuberculosis (TB) is high among household contacts (HHCs) of pre-extensively drug resistant (pre-XDR) TB and XDR-TB, data on yield of systematic longitudinal screening are lacking.
Roma Haresh Paryani, Vivek Gupta, Pramila Singh, Madhur Verma, Sabira Sheikh, Reeta Yadav, Homa Mansoor, Stobdan Kalon, Sriram Selvaraju, Mrinalini Das, Chinmay Laxmeshwar, Gabriella Ferlazzo, Petros Isaakidis   +12 more
doaj   +1 more source

The burden of pre-extensively and extensively drug-resistant tuberculosis among MDR-TB patients in the Amhara region, Ethiopia.

PLoS ONE, 2020
BACKGROUND:The emergence of pre-extensively and extensively drug-resistant tuberculosis (Pre-XDR/XDR-TB) is the major hurdle for TB prevention and care programs especially in developing countries like Ethiopia.
Agumas Shibabaw, Baye Gelaw, Wondwossen Gebreyes, Richard Robinson, Shu-Hua Wang, Belay Tessema   +5 more
doaj   +1 more source

Predictors of multidrug- and extensively drug-resistant tuberculosis in a high HIV prevalence community. [PDF]

PLoS ONE, 2010
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) have emerged in high-HIV-prevalence settings, which generally lack laboratory infrastructure for diagnosing TB drug resistance.
Jason R Andrews, N Sarita Shah, Darren Weissman, Anthony P Moll, Gerald Friedland, Neel R Gandhi   +5 more
doaj   +1 more source

RELATIONSHIP BETWEEN DETECTION OF TB AND TREATMENT OF MDR/XDR TB

International Journal of Infectious Diseases, 2023
Intro: Increasing the effectiveness of treatment of patients with multi- and extensively drug-resistant tuberculosis (MDR/XDR-TB) is an important public health objective.
V. Guseva, O. Otpushchennikova, N. Doktorova, I. Lizinfeld, L. Parolina, A. Samoylova   +5 more
doaj   +1 more source

Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015

Emerging Infectious Diseases, 2020
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) is an emerging threat to TB control in Ukraine, a country with the third highest XDR TB burden globally.
Matthias Merker, Elena Nikolaevskaya, Thomas A. Kohl, Barbara Molina-Moya, Olha Pavlovska, Patrik Brännberg, Andrii Dudnyk, Valentyna Stokich, Ivan Barilar, Iryna Marynova, Tetiana Filipova, Cristina Prat, Anders Sjöstedt, Jose Dominguez, Olena Rzhepishevska, Stefan Niemann   +15 more
doaj   +1 more source