Results 1 to 10 of about 22,610 (295)
Journal of Functional Biomaterials, 2022 Background: It has been shown in rabbit models that the sinus mucosa in contact with graft particles might experience a progressive thinning and perforations. The phenomenon depends on the graft used.
Yuki Omori +5 more
doaj +2 more sources
Frontiers in Immunology, 2023 IntroductionThe use of allogeneic hematopoietic cell transplantation (allo-HCT) for treating hematological disorders is increasing, but the development of graft-versus-host disease (GvHD) remains a major cause of morbidity and mortality.
Kristy E. Gilman +12 more
doaj +1 more source
Regenerative Effect of Mesenchymal Stem Cell on Cartilage Damage in a Porcine Model
Biomedicines, 2023 Osteoarthritis (OA) is a major public and animal health challenge with significant economic consequences. Cartilage degradation plays a critical role in the initiation and progression of degenerative joint diseases, such as OA.
Sheng-Chuan Lin +6 more
doaj +1 more source
The role of glycan characterisation in ATMP development and evaluation
Interdisciplinary Medicine, 2023 Advanced therapeutic medicinal products (ATMP) aim to transform treatment strategies for unmet clinical needs. ATMP development requires product standardisation, high‐quality consistent starting materials, and safety and efficacy, while reducing adverse ...
Kieran Joyce, Abhay Pandit
doaj +1 more source
The Innate Cellular Immune Response in Xenotransplantation
Frontiers in Immunology, 2022 Xenotransplantation is very attractive strategy for addressing the shortage of donors. While hyper acute rejection (HAR) caused by natural antibodies and complement has been well defined, this is not the case for innate cellular xenogeneic rejection.
Akira Maeda +14 more
doaj +1 more source
Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice
Frontiers in Immunology, 2018 Despite the increasing use of humanized mouse models to study new approaches of graft-versus-host disease (GVHD) prevention, the pathogenesis of xenogeneic GVHD (xGVHD) in these models remains misunderstood.
Grégory Ehx +16 more
doaj +1 more source
Cells, 2020 Over recent years, mesenchymal stromal cells (MSC) have gained immense attraction in immunotherapy, regenerative medicine and tissue engineering. MSC microenvironment modulation occurs through synergy of direct cell–cell contact, and secreted soluble ...
Adriana Torres Crigna +4 more
doaj +1 more source
Utilizing Xenogeneic Cells As a Therapeutic Agent for Treating Diseases
Cell Transplantation, 2021 The utilization of biologically produced cells to treat diseases is a revolutionary invention in modern medicine after chemically synthesized small molecule drugs and biochemically made protein drugs.
Chi-Ping Huang +2 more
doaj +1 more source
Annals of Surgery Open, 2022 Objective:. Evaluate long-term outcomes of abdominal wall reconstruction (AWR) using xenogeneic mesh in patients with Centers for Disease Control and Prevention (CDC) class III/IV defects.
Abbas M. Hassan, MD +4 more
doaj +1 more source
Scientific Reports, 2021 This study evaluated the use of bone ring technique with xenogeneic bone grafts in treating horizontal alveolar bone defects. In total, 11 patients in need of horizontal bone augmentation treatment before implant placement were included in this ...
Yude Ding +5 more
doaj +1 more source