Results 131 to 140 of about 93,386 (236)

The Pharmacology of the SLC15A4‐TASL Complex, an Emerging Target for the Treatment of Lupus

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT SLC15A4 is a member of the solute carrier superfamily that has been strongly linked to the pathogenesis of the auto‐immune disease SLE. The endo‐lysosomally localized SLC15A4 has traditionally been considered a proton‐dependent histidine and peptide transporter, but has also been shown to facilitate TLR7, 8, and 9 induced IFN‐alpha signaling ...
Alex L. Wilkinson   +5 more
wiley   +1 more source

Toxicity of Four Common Environmental Chemicals Across Caenorhabditis elegans Life Stages Supporting the One Health Concept

open access: yesEnvironmental Toxicology, Volume 41, Issue 8, Page 507-522, August 2026.
ABSTRACT Pesticides and pharmaceuticals are among the most common chemical groups in waterbodies and soils, and their universal distribution raises concerns about potential adverse effects on nontarget organisms and humans. Reproductive output disruption is of particular concern, as it transposes effects from the individual to the next generations at ...
Fábio Campos   +3 more
wiley   +1 more source

Xenbase: 25 years of integrating molecular and biomedical data from Xenopus. [PDF]

open access: yesGenetics
Chu S   +18 more
europepmc   +1 more source

Exploring the BICC1 Interactome in HEK293T Cells: Insights Into RNA‐Mediated Protein Networks and Biomolecular Condensates

open access: yesFASEB BioAdvances, Volume 8, Issue 8, August 2026.
Workflow for BICC1 interactome characterization in HEK293T cells. Cells expressing FLAG‐tagged BICC1 (full‐length or ΔSAM) were subjected to co‐immunoprecipitation under RNA‐preserved (−) or RNase‐treated (+) conditions (1). Interacting proteins were identified by LC–MS/MS (2) and analyzed through protein–protein interaction networks and functional ...
Heloísa Monteiro do Amaral‐Prado   +7 more
wiley   +1 more source

Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in <i>Xenopus</i>. [PDF]

open access: yesElife
Seo HS   +11 more
europepmc   +1 more source

Renal Phosphate Reabsorption in Humans Depends on at Least Three Distinct Transporters Unlike in Mice

open access: yesActa Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Aim Kidney excretion of phosphate is the gatekeeper of systemic phosphate homeostasis as evident from inborn and acquired diseases. Renal phosphate transporters are a promising target for phosphate‐lowering drugs, but molecular details of human kidney phosphate handling are largely unknown.
Ashley L. Fernandes   +10 more
wiley   +1 more source

Where Lineages Persist: Phylogenetic Patterns and Evolutionary Vulnerability in South Africa's Herpetofauna

open access: yesDiversity and Distributions, Volume 32, Issue 8, August 2026.
ABSTRACT Aim Conservation under the current global biodiversity crisis demands strategic prioritisation to maximise the impact of limited resources. This study aims to integrate evolutionary history, an often‐overlooked component of biodiversity, alongside extinction risk to identify priority species and regions, assessing both the feasibility and ...
J. Alexander Nieto Lawrence   +3 more
wiley   +1 more source

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