Molecular anatomy of emerging Xenopus left–right organizer at successive developmental stages
Abstract Background Vertebrate left–right symmetry breaking is preceded by formation of left–right organizer. In Amphibian, this structure is formed by gastrocoel roof plate, which emerges from superficial suprablastoporal cells. GRP is subdivided into medial area, which generates leftward flow by rotating monocilia and lateral Nodal1 expressing areas,
Natalia Petri+3 more
wiley +1 more source
Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (MutatoxR and Ames tests) [PDF]
The management of contaminated soils and wastes is a matter of considerable human concern. The present study evaluates the genotoxic potential of aqueous extracts of two soils (leachates) and of bottom ash resulting from municipal solid waste ...
Devaux, Alain+6 more
core +1 more source
Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells [PDF]
Exposure to particulate matter (PM) in ambient air is known to increase the risk of cardiovascular disorders and mortality. The cytotoxicity of PM is mainly due to the abnormal increase of reactive oxygen species (ROS), which damage cellular components ...
Bang, Woo Young+7 more
core +1 more source
The data presented here are related to the research article titled “Identification of circular RNAs and their alterations involved in developing male Xenopus laevis chronically exposed to atrazine” (Sai et al., 2018) [1].
Linlin Sai+11 more
doaj
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel+5 more
wiley +1 more source
Cell motility driving mediolateral intercalation in explants of Xenopus laevis [PDF]
In Xenopus, convergence and extension are produced by active intercalation of the deep mesodermal cells between one another along the mediolateral axis (mediolateral cell intercalation), to form a narrower, longer array.
Keller, Ray, Shih, John
core
A Model for Investigating Developmental Eye Repair in Xenopus Laevis [PDF]
Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration.
Kha, Cindy X.+3 more
core +2 more sources
Exploring the underlying mechanisms of Xenopus laevis embryonic cell cycle [PDF]
Cell cycle is an indispensable process in the proliferation and development. Despite significant efforts, global quantification and physical understanding are still challenging. In this study, we explored the mechanisms of Xenopus laevis embryonic cell cycle by quantifying the underlying landscape and flux.
arxiv
Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation [PDF]
During amphibian gastrulation, the embryo is transformed by the combined actions of several different tissues. Paradoxically, many of these morphogenetic processes can occur autonomously in tissue explants, yet the tissues in intact embryos must interact
Ewald, Andrew J.+4 more
core +2 more sources
Development of Antimicrobial Peptides from Amphibians
Since the discovery of magainins from the skin secretions of the African toad Xenopus laevis by Michael Zasloff in 1987, an increasing number of antimicrobial peptides (AMPs) has been identified in different anuran species and studied in detail [...]
Maria Luisa Mangoni, Bruno Casciaro
doaj +1 more source