Results 81 to 90 of about 157,699 (364)

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan   +5 more
wiley   +1 more source

Identification of a Candidate CD5 Homologue in the Amphibian Xenopus laevis [PDF]

open access: yes, 1995
We identified a novel T cell Ag in the South African clawed toad (Xenopus laevis) by a mAb designated 2B1. This Ag is present in relatively high levels on most thymocytes, approximately 65% of splenocytes, 55% of PBL, and 65% of intestinal lymphocytes ...
Cooper, Max D.   +5 more
core  

Biomonitoring of the genotoxic potential (micronucleus assay) and detoxifying activity (EROD induction) in the River Dadou (France), using the amphibian Xenopus laevis [PDF]

open access: yes, 2004
Within the framework of a general survey of the water quality of the river Dadou (Tarn, France), different physicochemical parameters were measured and an inventory of the fish population was made along the water course, around the Rassisse dam.With the ...
Gauthier, Laury   +3 more
core   +1 more source

Relating cell shape and mechanical stress in a spatially disordered epithelium using a vertex-based model [PDF]

open access: yesMathematical Medicine and Biology: A Journal of the IMA, dqx008 (2017), 2016
Using a popular vertex-based model to describe a spatially disordered planar epithelial monolayer, we examine the relationship between cell shape and mechanical stress at the cell and tissue level. Deriving expressions for stress tensors starting from an energetic formulation of the model, we show that the principal axes of stress for an individual ...
arxiv   +1 more source

A GC-MS/Single-Cell Method to Evaluate Membrane Transporter Substrate Specificity and Signaling

open access: yesFrontiers in Molecular Biosciences, 2021
Amino acid transporters play a vital role in metabolism and nutrient signaling pathways. Typically, transport activity is investigated using single substrates and competing amounts of other amino acids.
Stephen J. Fairweather   +6 more
doaj   +1 more source

Thyroid hormone signaling in the Xenopus laevis embryo is functional and susceptible to endocrine disruption.

open access: yesEndocrinology, 2012
Thyroid hormone (TH) is essential for vertebrate brain development. Most research on TH and neuronal development focuses on late development, mainly the perinatal period in mammals.
Jean-Baptiste Fini   +8 more
semanticscholar   +1 more source

Interspecific comparisons of anuran embryonic epidermal landscapes and energetic trade‐offs in response to changes in salinity

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Freshwater salinization is an emerging stressor in amphibian populations, and embryonic stages are most vulnerable. To better understand the variation in embryonic osmoregulation, we challenged embryos of two phylogenetically diverse anuran species, Xenopus laevis and Lithobates (Rana) sylvaticus, along a gradient of non‐lethal ...
Kourtnie Whitfield, Erica J. Crespi
wiley   +1 more source

Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro [PDF]

open access: yes, 1987
An extract from whole oocytes of Xenopus laevis was shown to transcribe somatic-type 5S RNA genes approximately 100-fold more efficiently than oocyte-type 5S RNA genes.
Eversole-Cire, Pamela   +4 more
core   +1 more source

Enigmatic Nodal and Lefty gene repertoire discrepancy: Latent evolutionary history revealed by vertebrate‐wide phylogeny

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
wiley   +1 more source

Probing the Xenopus laevis inner ear transcriptome for biological function

open access: yesBMC Genomics, 2012
Background The senses of hearing and balance depend upon mechanoreception, a process that originates in the inner ear and shares features across species.
Powers TuShun R   +3 more
doaj   +1 more source

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