Results 41 to 50 of about 9,272 (178)

Comparative transcriptome reveal the potential adaptive evolutionary genes in Andrias davidianus

open access: yesHereditas, 2018
To search the evidence of molecular evolution mechanism for aquatic and cave habitat in Andrias davidianus, the evolution analysis was carried out among several species transcriptome data.
Qiaomu Hu   +4 more
doaj   +1 more source

Xenopus Hybrids Provide Insight Into Cell and Organism Size Control

open access: yesFrontiers in Physiology, 2018
Determining how size is controlled is a fundamental question in biology that is poorly understood at the organismal, cellular, and subcellular levels. The Xenopus species, X. laevis and X. tropicalis differ in size at all three of these levels.
Romain Gibeaux   +4 more
doaj   +1 more source

Picroscope: low-cost system for simultaneous longitudinal biological imaging

open access: yesCommunications Biology, 2021
Ly et al. report a multi-well imaging system (the Picroscope) that can perform longitudinal bright-field z-stack imaging for 24 wells simultaneously. They demonstrate its capability by imaging zebrafish embryos, planaria worms, development of Xenopus ...
Victoria T. Ly   +18 more
doaj   +1 more source

A genetic map of Xenopus tropicalis

open access: yesDevelopmental Biology, 2011
We present a genetic map for Xenopus tropicalis, consisting of 2886 Simple Sequence Length Polymorphism (SSLP) markers. Using a bioinformatics-based strategy, we identified unique SSLPs within the X. tropicalis genome. Scaffolds from X. tropicalis genome assembly 2.0 (JGI) were scanned for Simple Sequence Repeats (SSRs); unique SSRs were then tested ...
Wells, Dan E.   +20 more
openaire   +2 more sources

Cas9-Based Genome Editing in Xenopus tropicalis [PDF]

open access: yes, 2014
Xenopus tropicalis has been developed as a model organism for developmental biology, providing a system offering both modern genetics and classical embryology. Recently, the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated (CRISPR/Cas) system for genome modification has provided an additional tool for Xenopus researchers to ...
Takuya, Nakayama   +6 more
openaire   +2 more sources

Generation and Care of Xenopus laevis and Xenopus tropicalis Embryos [PDF]

open access: yes, 2018
Robust and efficient protocols for fertilization and early embryo care of Xenopus laevis and Xenopus tropicalis are essential for experimental success, as well as maintenance and propagation of precious animal stocks. The rapid growth of the National Xenopus Resource has required effective implementation and optimization of these protocols.
Marcin, Wlizla   +2 more
openaire   +2 more sources

Chromatin immunoprecipitation and deep sequencing in Xenopus tropicalis and Xenopus laevis [PDF]

open access: yesMethods, 2014
Chromatin immunoprecipitation and deep sequencing (ChIP-SEQ) represents a powerful tool for identifying the genomic targets of transcription factors, chromatin remodeling factors, and histone modifications. The frogs Xenopus laevis and Xenopus tropicalis have historically been outstanding model systems for embryology and cell biology, with emerging ...
Andrea E, Wills   +3 more
openaire   +2 more sources

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho   +2 more
wiley   +1 more source

Deep transcriptome profiling reveals limited conservation of A-to-I RNA editing in Xenopus

open access: yesBMC Biology, 2023
Background Xenopus has served as a valuable model system for biomedical research over the past decades. Notably, ADAR was first detected in frog oocytes and embryos as an activity that unwinds RNA duplexes. However, the scope of A-to-I RNA editing by the
Tram Anh Nguyen   +11 more
doaj   +1 more source

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