Results 21 to 30 of about 21,110 (223)
Frontiers in Cell and Developmental Biology, 2023 The incomplete silencing of exogenous transcription factors (TFs) and the lack of endogenous counterpart activation hampers the application of porcine induced pluripotent stem cells (piPSCs).
Meng Zhou +12 more
doaj +1 more source
Xenotransplantation public perceptions: rather cells than organs. [PDF]
, 2003 The aim of this study was to describe some of the factors that might play a role in influencing attitude to xenotransplantation: first, the consideration of receiving cells and tissue from xenotransplants in relation to whole xeno-organs; secondly, the ...
Ranstam, Jonas +5 more
core +1 more source
Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain [PDF]
, 2023 2023 Acuerdos transformativos CRUEBackground: The shortage of available transplant organs has made it necessary to search for alternatives, one of which is xenotransplantation.
Fidel San Román‐Ascaso +37 more
core +1 more source
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs
Disease Models & Mechanisms, 2018 Miniature pigs have advantages over rodents in modeling atherosclerosis because their cardiovascular system and physiology are similar to that of humans. Apolipoprotein E (ApoE) deficiency has long been implicated in cardiovascular disease in humans.
Bin Fang +19 more
doaj +1 more source
Experimental multivisceral xenotransplantation [PDF]
, 2008 Background: Organ shortage impairs the proposition of multivisceral transplantation to treat multiple organ failure. Interspecies (xeno) transplantation is a valid solution for organ shortage; however, suitable models of this advance are lacking.
COSTA, Anderson da Costa Lino +8 more
core +1 more source
Immunoglobulin G profile in hyperacute rejection after multivisceral xenotransplantation [PDF]
, 2012 Galvao FHF, Soler W, Pompeu E, Waisberg DR, Mello ES, Costa ACL, Teodoro W, Velosa AP, Capelozzi VL, Antonangelo L, Catanozi S, Martins A, Malbouisson LMS, Cruz RJ, Figueira ER, Filho JAR, Chaib E, D'Albuquerque LAC.
Chaib, Eleazar +17 more
core +1 more source
Korean attitudes to Xenotransplantation: A survey conducted in 2009 [PDF]
, 2018 Background: Xenotransplantation research has been being actively conducted in Korea. However, there are numbers of socio-ethical issues involved in this research, and it is necessary to know public attitudes toward the research, inducing &quot ...
권복규
core +1 more source
Kidney xenotransplantation [PDF]
Kidney International, 2014 Xenotransplantation using pigs as donors offers the possibility of eliminating the chronic shortage of donor kidneys, but there are several obstacles to be overcome before this goal can be achieved. Preclinical studies have shown that, while porcine renal xenografts are broadly compatible physiologically, they provoke a complex rejection process ...
Cowan, PJ, Cooper, DKC, d'Apice, AJF
openaire +3 more sources
Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting
Scientific Reports, 2017 Complement protein C3 is the pivotal component of the complement system. Previous studies have demonstrated that C3 has implications in various human diseases and exerts profound functions under certain conditions.
Wei Zhang +10 more
doaj +1 more source
Journal of British Surgery, 2000 Abstract Background The success of clinical transplantation has led to a large discrepancy between donor organ availability and demand; considerable pressure exists to develop an alternative source of organs.
Soin, B, Vial, C, Friend, P
openaire +3 more sources