Results 11 to 20 of about 1,075 (125)

Pregnant patient with Xp11.2/transcription factor E3 translocation renal cell carcinoma: a case report and literature review [PDF]

Frontiers in Oncology
MiT family translocation renal cell carcinomas (tRCCs) primarily include Xp11.2/transcription factor E3 (TFE3) gene fusion-associated renal cell carcinoma (Xp11.2 tRCC) and t(6;11)/TFEB gene fusion-associated RCC.
Yanchen Wang, Xiaoyan Guo, Zhe Meng, Yong Cui, Yaofei Sun   +4 more
doaj   +2 more sources

Four years of natural progressive course: A rare case report of juvenile Xp11.2 translocations renal cell carcinoma with TFE3 gene fusion [PDF]

Open Medicine
Renal cell carcinoma (RCC) with TFE3 gene fusion caused by Xp11.2 translocations is a rare RCC subtype. This tumor is typically seen in children, comprising 20‒40% of overall RCC cases compared to 1‒1.6% observed in adults.
Hu Liang, Li Lina, Li Angcheng, Tong Jianyong   +3 more
doaj   +2 more sources

ASPSCR1: TFE3 Fusion‐Positive Epithelioid Angiomyolipoma/PEComa Lacking Melanocytic Markers: A Case Report [PDF]

IJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Epithelioid angiomyolipoma is a rare perivascular epithelioid cell tumor subtype with malignant potential. Its morphology mimics renal cell carcinoma, posing diagnostic challenges. Half of these cases harbor TSC1/TSC2 alterations, and a small subset features TFE3 rearrangements, mutually exclusive of TSC mutations.
Yuka Kondo, Yoji Nagashima, Kenji Zennami, Megumi Sato, Sayaka Sumiyoshi, Akihiko Sugimoto, Madoka Isomura, Kiyoshi Takahara, Sachiko Minamiguchi   +8 more
wiley   +2 more sources

MiT family translocation renal cell carcinoma with retroperitoneal metastasis in childhood: a case report [PDF]

Frontiers in Pediatrics, 2023
RCC accounts for only 0.1%–0.3% of all kidney tumors and 2%–6% of malignant kidney tumors in children. Accounting for approximately one-third of the total number of cases in children and adolescents with RCC, Xp11.2 tRCC is the most common subtype of the
Kaihang Yang, Yuhao Ma, Shuyang Dai, Rui Dong   +3 more
doaj   +2 more sources

Renal cell carcinoma associated with XP11.2 translocation: A case report and literature review [PDF]

Urology Case Reports
Renal cell carcinoma (RCC) associated with XP11.2 translocation is an exceedingly rare subtype of RCC. A 27-year-old female presented with a 6.7cm mass and underwent a robotic-assisted left radical nephrectomy with uneventful recovery. Pathology revealed
Bader Alsaikhan, Saud AlHussayen, Ebtesam Almajed, Abdullah Alghuraibi, Khaled Almodeth, Noura Al Oudah, Abdulrahman K. Alabdulsalam   +6 more
doaj   +2 more sources

Clinicopathological features and prognosis of TFE3-positive renal cell carcinoma [PDF]

Frontiers in Oncology, 2022
BackgroundThis study aimed to investigate the expression profile of TFE3 in renal cell carcinoma (RCC) and the clinicopathological features as well as prognosis of TFE3-positive RCC.MethodsTissue sections from 796 patients with RCC were collected for ...
Xiang Dong, Yuxin Chen, Jun Pan, Wenliang Ma, Peng Zhou, Ming Chen, Hongqian Guo, Weidong Gan   +7 more
doaj   +2 more sources

Remarkable Response to Immunotherapy and VEGFR Inhibitor in Xp11 Translocation Renal Cell Carcinoma in a 17‐Year‐Old Adolescent [PDF]

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Background Xp11 translocation renal cell carcinoma (tRCC) is a rare and aggressive renal cancer characterized by gene fusion involving TFE3. It accounts for < 5% of renal cancers and shows variable responses to conventional antivascular endothelial growth factor therapies.
Piyarat Limpawittayakul, Narongchai Teerayathanakul, Farid Cherbal   +2 more
wiley   +2 more sources

Case Report: Clinical complete response of advanced renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion by treated by camrelizumab and axitinib: A rare case report [PDF]

Frontiers in Pharmacology, 2022
Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusions is a rare subtype of renal tumor. This entity predominantly occurs in juveniles, but rarely in adults.
Juping Zhao, Kun Dai, Jialing Xie, Chen Fang, Na Chen, Jun Dai, Danfeng Xu   +6 more
doaj   +2 more sources

The Relevance of the Virchow Node and Virchow Triad in Renal Cancer Diagnosis [PDF]

Clinics and Practice
Background: The purpose of this article is to overview the clinical significance of left supraclavicular adenopathy and review the etiology of inferior vena cava (IVC) thrombosis, starting from a presentation of a rare case of renal cell carcinoma (RCCs)
Luiza-Roxana Dorobantu-Lungu, Viviana Dinca, Andrei Gegiu, Dan Spataru, Andreea Toma, Luminita Welt, Mihaela Florentina Badea, Constantin Caruntu, Cristian Scheau, Ilinca Savulescu-Fiedler   +9 more
doaj   +2 more sources

Surgical management of giant Xp11.2 translocation renal cell carcinoma with multivisceral invasion: a case report of en bloc resection and targeted-immunotherapy success [PDF]

Frontiers in Oncology
A 36-year-old man presented with a 1-month history of abdominal distension and a 3-day palpable mass. Imaging demonstrated a 20-cm left renal tumor with adjacent organ infiltration and suspicious lymphadenopathy, radiologically suggestive of sarcoma or ...
Bohan Luo, Han Luo
doaj   +2 more sources