Results 21 to 30 of about 1,075 (125)

A Rare Case of TFE3‐Rearranged and SMARCB1‐Mutated Renal Cell Carcinoma: Diagnostic and Therapeutic Complexities [PDF]

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Renal cell carcinoma (RCC) represents the majority of kidney malignancies, with clear cell RCC being the most common subtype. However, recent advances in tumor genomics have refined RCC classification, highlighting rare molecular subtypes such as TFE3‐rearranged and SMARCB1‐deficient RCCs.
Paul J. Pecorin, Nyembezi Dhliwayo, Trevor Christ, Thomas Westbrook, Harleen Khatra   +4 more
wiley   +2 more sources

Renal cell carcinoma in the contralateral kidney with TFE3 gene translocation following chemotherapy for childhood nephroblastoma: A case report and literature review

Clinical Case Reports, Volume 11, Issue 11, November 2023., 2023
Key Clinical Message Renal cell carcinoma as a secondary malignant neoplasm is relatively rare; however, the possibility of secondary renal cell carcinoma following chemoradiotherapy for childhood nephroblastoma should be considered. Abstract The occurrence of secondary renal cell carcinoma (RCC) following chemoradiotherapy for nephroblastoma is ...
Shunsuke Fujisawa, Junya Furukawa, Takuto Hara, Keiske Okada, Kouji Chiba, Yuzo Nakano, Toshiki Hyodo, Yoji Nagashima, Masato Fujisawa   +8 more
wiley   +1 more source

Preoperative neutrophil-to-lymphocyte ratio predicts the surgical outcome of Xp11.2 translocation/TFE3 renal cell carcinoma patients

BMC Urology, 2018
Background The preoperative neutrophil-to-lymphocyte ratio (NLR), C-reactive protein/albumin ratio (CRP/Alb ratio) and platelet-to-lymphocyte ratio (PLR) have been demonstrated to predict the clinical outcome of various human cancer, including renal cell
Sezim Agizamhan, Feng Qu, Ning Liu, Jing Sun, Wei Xu, Lihua Zhang, Hongqian Guo, Weidong Gan   +7 more
doaj   +1 more source

Estradiol increases risk of topoisomerase IIβ-mediated DNA strand breaks to initiate Xp11.2 translocation renal cell carcinoma

Cell Communication and Signaling, 2021
Background Xp11.2 translocation renal cell carcinoma (tRCC) is defined by translocation of the transcription factor E3 (TFE3) gene located on chromosome Xp11.2.
Qiancheng Shi, Ning Liu, Lei Yang, Yi Chen, Yanwen Lu, Hongqian Guo, Xiaodong Han, Dongmei Li, Weidong Gan   +8 more
doaj   +1 more source

Imaging Characteristics of Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusions in Children

Zhongliu Fangzhi Yanjiu, 2021
Objective To investigate the imaging characteristics of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion. Methods We retrospectively analyzed the clinical and imaging data of five children with Xp11.2 tRCC confirmed by surgery ...
PENG Fei, YAN Xueqiang, SHAO Jianbo
doaj   +1 more source

Gender difference analysis of Xp11.2 translocation renal cell carcinomas’s attack rate: a meta-analysis and systematic review

BMC Urology, 2020
Background Xp11.2 translocation renal cell carcinoma (tRCC) is recently recognized. As Xp11.2 tRCC involved gene translocation and fusion in X chromosome and the number of X chromosomes in female is twice of male, we wondered whether the gender ...
Wenyuan Zhuang, Ning Liu, Hongqian Guo, Chunni Zhang, Weidong Gan   +4 more
doaj   +1 more source

Contrast-enhanced ultrasound findings of adult renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion: comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma

Cancer Imaging, 2019
Background To investigate the contrast-enhanced ultrasound (CEUS) findings of renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2/TFE3) in adult patients by comparison with those of clear cell RCC (ccRCC) and ...
Shuping Wei, Fuli Tian, Qiuyuan Xia, Pengfei Huang, Yidan Zhang, Zhichao Xia, Min Wu, Bin Yang   +7 more
doaj   +1 more source

Bilateral Xp11.2 translocation renal cell carcinoma: a case report

BMC Urology, 2018
Background Xp11.2 translocation renal cell carcinoma (RCC) is a rare variety of a kidney neoplasm. We report a case of bilateral Xp11.2 translocation RCC occurring metachronously and discuss this very rare entity with reference to the literature.
Takashi Karashima, Takahira Kuno, Naoto Kuroda, Hirofumi Satake, Satoshi Fukata, Masakazu Chikazawa, Chiaki Kawada, Ichiro Yamasaki, Taro Shuin, Makoto Hiroi, Keiji Inoue   +10 more
doaj   +1 more source

PD-L1 expression in Xp11.2 translocation renal cell carcinoma: Indicator of tumor aggressiveness

Scientific Reports, 2017
Programmed death ligand-1 (PD-L1), a promising antitumor target, has proven clinical value against many malignancies. However, the PD-L1 content of Xp11.2 translocation renal cell carcinoma (Xp11.2 RCC) and its correlation with clinical outcomes remain ...
Kun Chang, Yuanyuan Qu, Bo Dai, Jian-Yuan Zhao, Hualei Gan, Guohai Shi, Yiping Zhu, Yijun Shen, Yao Zhu, Hailiang Zhang, Dingwei Ye   +10 more
doaj   +1 more source

Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusions: Clinical Features, Treatments and Prognosis. [PDF]

PLoS ONE, 2016
To investigate the clinical characteristics, treatments and prognosis of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions (Xp11.2 tRCC), the epidemiological features and treatment results of 34 cases of Xp11.2 tRCC, which were ...
Ning Liu, Zhen Wang, Weidong Gan, Lei Xiong, Baolei Miao, Xiancheng Chen, Hongqian Guo, Dongmei Li   +7 more
doaj   +1 more source