Results 31 to 40 of about 1,075 (125)

Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: an adult case report and literature review

Journal of International Medical Research, 2020
Renal cell carcinoma (RCC) associated with Xp11.2 translocation/transcription factor E3 ( TFE3 ) gene fusion is a rare and independent subtype of RCC included in the classification of MiT (microphthalmia-associated transcriptional factor) family ...
Yuxiong Wang, Yuantao Wang, Mingliang Feng, Xin Lian, Yongsheng Lei, Honglan Zhou   +5 more
doaj   +1 more source

Low expression of TRAF3IP2-AS1 promotes progression of NONO-TFE3 translocation renal cell carcinoma by stimulating N 6-methyladenosine of PARP1 mRNA and downregulating PTEN

Journal of Hematology & Oncology, 2021
Background NONO-TFE3 translocation renal cell carcinoma (NONO-TFE3 tRCC) is one subtype of RCCs associated with Xp11.2 translocation/TFE3 gene fusions RCC (Xp11.2 tRCCs). Long non-coding RNA (lncRNA) has attracted great attention in cancer research.
Lei Yang, Yi Chen, Ning Liu, QianCheng Shi, Xiaodong Han, Weidong Gan, Dongmei Li   +6 more
doaj   +1 more source

TFE3‐DualNet: An Interpretable Foundation Model‐Based Deep Learning Ensemble for Diagnosing TFE3‐Rearranged Renal Cell Carcinoma From Whole‐Slide Images in a Two‐Center Cohort

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is a rare, aggressive subtype that predominantly affects adolescents and young adults. Its marked morphologic heterogeneity can delay recognition and downstream confirmatory testing.
Yu‐Hang Chen, Quan‐Hui Xu, Hao‐Hua Yao, Ke‐Zhi Liu, Cheng‐Peng Gui, Liang‐Min Fu, Ying‐Han Wang, Jiang‐Quan Zhu, Jun‐Cai Li, Min‐Yu Chen, Kang‐Bo Huang, Han‐Sen Lin, Bing Liao, Yun Cao, Jin‐Huan Wei, Peng‐Ju Li, Jun‐Hang Luo, Jia‐Zheng Cao   +17 more
wiley   +1 more source

Unexpected Cervical Lymph Node Metastasis Revealing TFE3‐Rearranged Renal Cell Carcinoma: Intraoperative Cytologic Clues to an Occult Renal Primary

Diagnostic Cytopathology, Volume 54, Issue 7, Page 538-541, July 2026.
ABSTRACT TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is a rare subtype of renal carcinoma that may present diagnostic challenges in cytologic specimens, particularly when metastatic disease represents the initial clinical manifestation. We report the case of a 72‐year‐old man presenting with bulky cervical lymphadenopathy clinically suspicious for
Marc P. Pusztaszeri
wiley   +1 more source

老年双侧Xp11.2易位/TFE3基因融合相关性肾癌1例诊断与治疗

Zhongguo shiyan zhenduanxue, 2021
Xp11.2易位/TFE3基因融合相关性肾癌(renal carcinoma associated with Xp11.2translocations/TFE-3gene fusions,Xp11.2RCC)十分罕见,其特点是Xp11.2染色体易位造成了转录因子E3(TFE3)与多种不同的基因融合,从而导致融合型TFE3蛋白的表达异常升高,故被称为Xp11.2易位/TFE3基因融合相关性肾癌[1]。de Jong等[1]于1986年首次报道 ...
王成燃, 谷欣权, 李杨, 孟繁萍
doaj  

Temsirolimus in the treatment of renal cell carcinoma associated with Xp11.2 translocation/TFE gene fusion proteins: a case report and review of literature

Rare Tumors, 2009
Xp11.2 translocation renal cell carcinomas (TRCCs) are a rare family of tumors newly recognized by the World Health Organization (WHO) in 2004. These tumors result in the fusion of partner genes to the TFE3 gene located on Xp11.2. They are most common in
James Brown, Nidia Messias, Teresa Coleman, Jigarkumar Parikh   +3 more
doaj   +1 more source

Magnetic resonance imaging and computed tomography characteristics of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion. [PDF]

PLoS ONE, 2014
PURPOSE: To characterize Xp11.2 translocation renal cell carcinoma (RCC) using magnetic resonance imaging (MRI) and computed tomography (CT). METHODS: This study retrospectively collected the MRI and CT data of twelve patients with Xp11.2 translocation ...
Wei Wang, Jianhui Ding, Yuan Li, Chaofu Wang, Liangping Zhou, Hui Zhu, Weijun Peng   +6 more
doaj   +1 more source

Rapidly progressing renal cell carcinoma associated with Xp11.2 translocations: a case report

Journal of Medical Case Reports, 2012
Introduction Renal cell carcinoma associated with Xp11.2 translocations is frequently reported in children, but adult-onset is rare. Here, the case of an adult male who developed a renal cell carcinoma associated with Xp11.2 translocations is presented ...
Morii Akihiro, Fujiuchi Yasuyoshi, Nomoto Kazuhiro, Komiya Akira, Fuse Hideki   +4 more
doaj   +1 more source

Emerging Role of ctDNA Fragmentomics and Epigenetic Signatures in the Early Detection, Minimal Residual Disease Assessment, and Precision Monitoring of Renal Cell Carcinoma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Renal cell carcinoma (RCC) presents a significant global health challenge, with a substantial proportion of patients diagnosed with advanced or metastatic disease due to the limitations of current diagnostic imaging and the lack of validated non‐invasive biomarkers.
Hossam Kamli, Najeeb Ullah Khan
wiley   +1 more source

Recent developments in eosinophilic renal neoplasms: what's new, true and important?

Histopathology, Volume 88, Issue 1, Page 166-192, January 2026.
Recent developments and acquired knowledge on newer renal entities with eosinophilic cytoplasm opened insights into the clinical, pathological, immunohistochemical, molecular, epidemiological aspects, and the prognosis of these entities. We emphasize the role of routine morphology, aided by appropriate and select immunohistochemistry, as essential keys
Kiril Trpkov, Farshid Siadat, Rola Saleeb   +2 more
wiley   +1 more source