Results 11 to 20 of about 787 (112)

Case Report: Clinical complete response of advanced renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion by treated by camrelizumab and axitinib: A rare case report [PDF]

Frontiers in Pharmacology, 2022
Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusions is a rare subtype of renal tumor. This entity predominantly occurs in juveniles, but rarely in adults.
Juping Zhao, Kun Dai, Jialing Xie, Chen Fang, Na Chen, Jun Dai, Danfeng Xu   +6 more
doaj   +2 more sources

Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: an adult case report and literature review [PDF]

Journal of International Medical Research, 2020
Renal cell carcinoma (RCC) associated with Xp11.2 translocation/transcription factor E3 ( TFE3 ) gene fusion is a rare and independent subtype of RCC included in the classification of MiT (microphthalmia-associated transcriptional factor) family ...
Yuxiong Wang, Yuantao Wang, Mingliang Feng, Xin Lian, Yongsheng Lei, Honglan Zhou   +5 more
doaj   +2 more sources

Bilateral Xp11.2 translocation renal cell carcinoma: a case report [PDF]

BMC Urology, 2018
Background Xp11.2 translocation renal cell carcinoma (RCC) is a rare variety of a kidney neoplasm. We report a case of bilateral Xp11.2 translocation RCC occurring metachronously and discuss this very rare entity with reference to the literature.
Takashi Karashima, Takahira Kuno, Naoto Kuroda, Hirofumi Satake, Satoshi Fukata, Masakazu Chikazawa, Chiaki Kawada, Ichiro Yamasaki, Taro Shuin, Makoto Hiroi, Keiji Inoue   +10 more
doaj   +2 more sources

Gender difference analysis of Xp11.2 translocation renal cell carcinomas’s attack rate: a meta-analysis and systematic review [PDF]

BMC Urology, 2020
Background Xp11.2 translocation renal cell carcinoma (tRCC) is recently recognized. As Xp11.2 tRCC involved gene translocation and fusion in X chromosome and the number of X chromosomes in female is twice of male, we wondered whether the gender ...
Wenyuan Zhuang, Ning Liu, Hongqian Guo, Chunni Zhang, Weidong Gan   +4 more
doaj   +2 more sources

Molecular Heterogeneity of Xp11.2 Translocation Renal Cell Carcinoma: The Correlation Between Split Signal Pattern in FISH and Prognosis [PDF]

Cancer Management and Research, 2021
Yiqi Zhu,1,* Xiaohong Pu,2,* Xiang Dong,3 Changwei Ji,1 Hongqian Guo,1 Dongmei Li,4,5 Xiaozhi Zhao,1 Weidong Gan1 1Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, People ...
Zhu Y, Pu X, Dong X, Ji C, Guo H, Li D, Zhao X, Gan W   +7 more
doaj   +2 more sources

Percutaneous radiofrequency ablation on a Xp11.2 Translocation Renal Cell Carcinoma: A case report [PDF]

Urology Case Reports, 2020
Xp11.2 Translocation Renal Cell Carcinoma is a very rare subtype of renal neoplasm. The present report describes the first confirmed reported case of percutaneous ablation of this subtype of tumor.
Alexandre Fligelman Kanas, Marcello Silveira Rovella, Mauricio Ruettimann Liberato de Moura, Katia Ramos Moreira Leite, Miguel Srougi, Marcos Roberto de Menezes   +5 more
doaj   +2 more sources

Surgical management of giant Xp11.2 translocation renal cell carcinoma with multivisceral invasion: a case report of en bloc resection and targeted-immunotherapy success [PDF]

Frontiers in Oncology
A 36-year-old man presented with a 1-month history of abdominal distension and a 3-day palpable mass. Imaging demonstrated a 20-cm left renal tumor with adjacent organ infiltration and suspicious lymphadenopathy, radiologically suggestive of sarcoma or ...
Bohan Luo, Han Luo
doaj   +2 more sources

ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion

Molecular Oncology, 2023
Loss or downregulation of major histocompatibility complex class I (MHC‐I) contributes to tumor immune evasion. We previously demonstrated that angiopoietin‐like protein 2 (ANGPTL2) promotes tumor progression using a Xp11.2 translocation renal cell ...
Tsuyoshi Kadomatsu, Chiaki Hara, Ryoma Kurahashi, Haruki Horiguchi, Jun Morinaga, Keishi Miyata, Sohtaro Kurano, Hisashi Kanemaru, Satoshi Fukushima, Kimi Araki, Masaya Baba, W. Marston Linehan, Tomomi Kamba, Yuichi Oike   +13 more
doaj   +2 more sources

Preoperative neutrophil-to-lymphocyte ratio predicts the surgical outcome of Xp11.2 translocation/TFE3 renal cell carcinoma patients [PDF]

BMC Urology, 2018
Background The preoperative neutrophil-to-lymphocyte ratio (NLR), C-reactive protein/albumin ratio (CRP/Alb ratio) and platelet-to-lymphocyte ratio (PLR) have been demonstrated to predict the clinical outcome of various human cancer, including renal cell
Sezim Agizamhan, Feng Qu, Ning Liu, Jing Sun, Wei Xu, Lihua Zhang, Hongqian Guo, Weidong Gan   +7 more
doaj   +2 more sources

PD-L1 expression in Xp11.2 translocation renal cell carcinoma: Indicator of tumor aggressiveness [PDF]

Scientific Reports, 2017
Programmed death ligand-1 (PD-L1), a promising antitumor target, has proven clinical value against many malignancies. However, the PD-L1 content of Xp11.2 translocation renal cell carcinoma (Xp11.2 RCC) and its correlation with clinical outcomes remain ...
Kun Chang, Yuanyuan Qu, Bo Dai, Jian-Yuan Zhao, Hualei Gan, Guohai Shi, Yiping Zhu, Yijun Shen, Yao Zhu, Hailiang Zhang, Dingwei Ye   +10 more
doaj   +2 more sources