Results 21 to 30 of about 787 (112)

Papillary Renal Cell Carcinoma in Transplanted Kidney and Xp11.2 Translocation/ Transcription Factor E3-Rearranged Renal Cell Carcinoma in the Native Kidney: A Case Report [PDF]

Journal of the Korean Society of Radiology
Concomitant renal cell carcinomas (RCC) of both native and allograft kidneys are extremely rare, and only a few cases have been reported in the available English literature.
Min Hye Kim, Kyeong Ah Kim, Jeong Woo Kim, Seok Young Lee, Jae Woong Choi   +4 more
doaj   +2 more sources

Temsirolimus in the treatment of renal cell carcinoma associated with Xp11.2 translocation/TFE gene fusion proteins: a case report and review of literature

Rare Tumors, 2009
Xp11.2 translocation renal cell carcinomas (TRCCs) are a rare family of tumors newly recognized by the World Health Organization (WHO) in 2004. These tumors result in the fusion of partner genes to the TFE3 gene located on Xp11.2. They are most common in
Jigarkumar Parikh, Nidia Messias
exaly   +3 more sources

Contrast-enhanced ultrasound findings of adult renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion: comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma [PDF]

Cancer Imaging, 2019
Background To investigate the contrast-enhanced ultrasound (CEUS) findings of renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2/TFE3) in adult patients by comparison with those of clear cell RCC (ccRCC) and ...
Shuping Wei, Fuli Tian, Qiuyuan Xia, Pengfei Huang, Yidan Zhang, Zhichao Xia, Min Wu, Bin Yang   +7 more
doaj   +2 more sources

TFE3 fusions escape from controlling of mTOR signaling pathway and accumulate in the nucleus promoting genes expression in Xp11.2 translocation renal cell carcinomas [PDF]

Journal of Experimental & Clinical Cancer Research, 2019
Background Xp11.2 translocation renal cell carcinoma (tRCC) is mainly caused by translocation of the TFE3 gene located on chromosome Xp11.2 and is characterized by overexpression of the TFE3 fusion gene. Patients are diagnosed with tRCC usually before 45 
Xiaoqin Yin, Bo Wang, Weidong Gan, Wenyuan Zhuang, Zou Xiang, Xiaodong Han, Dongmei Li   +6 more
doaj   +2 more sources

Clinicopathological features and prognosis of TFE3-positive renal cell carcinoma

Frontiers in Oncology, 2022
BackgroundThis study aimed to investigate the expression profile of TFE3 in renal cell carcinoma (RCC) and the clinicopathological features as well as prognosis of TFE3-positive RCC.MethodsTissue sections from 796 patients with RCC were collected for ...
Xiang Dong, Yuxin Chen, Jun Pan, Wenliang Ma, Peng Zhou, Ming Chen, Hongqian Guo, Weidong Gan   +7 more
doaj   +1 more source

Renal cell carcinoma in the contralateral kidney with TFE3 gene translocation following chemotherapy for childhood nephroblastoma: A case report and literature review

Clinical Case Reports, Volume 11, Issue 11, November 2023., 2023
Key Clinical Message Renal cell carcinoma as a secondary malignant neoplasm is relatively rare; however, the possibility of secondary renal cell carcinoma following chemoradiotherapy for childhood nephroblastoma should be considered. Abstract The occurrence of secondary renal cell carcinoma (RCC) following chemoradiotherapy for nephroblastoma is ...
Shunsuke Fujisawa, Junya Furukawa, Takuto Hara, Keiske Okada, Kouji Chiba, Yuzo Nakano, Toshiki Hyodo, Yoji Nagashima, Masato Fujisawa   +8 more
wiley   +1 more source

Sarcomatoid renal cell tumor harboring a novel BYSL::TFEB fusion with concurrent TFEB amplification

Genes, Chromosomes and Cancer, Volume 62, Issue 6, Page 353-360, June 2023., 2023
Abstract Transcription factor EB (TFEB)‐rearranged renal cell carcinoma (RCC) exhibits diverse gene fusion patterns and heterogeneous clinicopathologic features. Rare TFEB‐amplified RCCs have been described recently and are associated with a more aggressive clinical course. Herein, we report a case of an 86‐year‐old man with a solid 9.2‐cm kidney tumor
Ruihe Lin, Elizaveta Flerova, Christine E. Wamsley, Peter A. McCue, Costas D. Lallas, Wei Jiang, Jialing Huang, Zi‐Xuan Wang, Li Li   +8 more
wiley   +1 more source

A novel VCP::TFE3 gene fusion resulting from t(X;9)(p11.23;p13.3) chromosome translocation in TFE3 rearranged renal cancer cell carcinoma

Genes, Chromosomes and Cancer, Volume 62, Issue 6, Page 361-366, June 2023., 2023
Abstract Renal cell carcinoma (RCC) with rearrangement of transcription factor for immunoglobulin heavy‐chain enhancer 3 (TFE3; TFE3‐rearranged RCC) at Xp11.2 is a rare tumor entity but the most frequent among the microphthalmia transcription factor family translocation RCCs.
Marie Auvray Kuentz, Hélène Blons, Anne Paule Gimenez‐Roqueplo, Pierre‐Alexandre Just, Pierre Laurent‐Puig, Arnaud Mejean, Stéphane Oudard, Virginie Verkarre   +7 more
wiley   +1 more source

Tumor biology, biomarkers, and liquid biopsy in pediatric renal tumors

Pediatric Blood &Cancer, Volume 70, Issue S2, May 2023., 2023
Abstract The expansion of knowledge regarding driver mutations for Wilms tumor (WT) and malignant rhabdoid tumor of the kidney (MRT) and various translocations for other pediatric renal tumors opens up new possibilities for diagnosis and treatment.
Amy L. Walz, Mariana Maschietto, Brian Crompton, Nicholas Evageliou, David Dix, Godelieve Tytgat, Manfred Gessler, David Gisselsson, Najat C. Daw, Jenny Wegert   +9 more
wiley   +1 more source

An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles

Journal of Extracellular Vesicles, Volume 12, Issue 2, February 2023., 2023
Abstract Extracellular vesicles (EV) are membranous particles secreted by all cells and found in body fluids. Established EV contents include a variety of RNA species, proteins, lipids and metabolites that are considered to reflect the physiological status of their parental cells.
Karina Barreiro, Abigail C. Lay, German Leparc, Van Du T. Tran, Marcel Rosler, Lusyan Dayalan, Frederic Burdet, Mark Ibberson, Richard J. M. Coward, Tobias B. Huber, Bernhard K. Krämer, Denis Delic, Harry Holthofer   +12 more
wiley   +1 more source