Results 11 to 20 of about 673 (120)

Percutaneous radiofrequency ablation on a Xp11.2 Translocation Renal Cell Carcinoma: A case report [PDF]

open access: yesUrology Case Reports, 2020
Xp11.2 Translocation Renal Cell Carcinoma is a very rare subtype of renal neoplasm. The present report describes the first confirmed reported case of percutaneous ablation of this subtype of tumor.
Alexandre Fligelman Kanas   +5 more
doaj   +2 more sources

Surgical management of giant Xp11.2 translocation renal cell carcinoma with multivisceral invasion: a case report of en bloc resection and targeted-immunotherapy success [PDF]

open access: yesFrontiers in Oncology
A 36-year-old man presented with a 1-month history of abdominal distension and a 3-day palpable mass. Imaging demonstrated a 20-cm left renal tumor with adjacent organ infiltration and suspicious lymphadenopathy, radiologically suggestive of sarcoma or ...
Bohan Luo, Han Luo
doaj   +2 more sources

ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion

open access: yesMolecular Oncology, 2023
Loss or downregulation of major histocompatibility complex class I (MHC‐I) contributes to tumor immune evasion. We previously demonstrated that angiopoietin‐like protein 2 (ANGPTL2) promotes tumor progression using a Xp11.2 translocation renal cell ...
Tsuyoshi Kadomatsu   +13 more
doaj   +2 more sources

Temsirolimus in the treatment of renal cell carcinoma associated with Xp11.2 translocation/TFE gene fusion proteins: a case report and review of literature

open access: yesRare Tumors, 2009
Xp11.2 translocation renal cell carcinomas (TRCCs) are a rare family of tumors newly recognized by the World Health Organization (WHO) in 2004. These tumors result in the fusion of partner genes to the TFE3 gene located on Xp11.2. They are most common in
James Brown   +3 more
doaj   +3 more sources

Computational analysis of pathological images enables a better diagnosis of TFE3 Xp11.2 translocation renal cell carcinoma [PDF]

open access: yesNature Communications, 2020
Translocation renal cell carcinoma is an aggressive form of renal cancer that is often misdiagnosed to other subtypes. Here the authors demonstrated that by using machine learning and H&E stained whole-slide images, an accurate diagnose of this ...
Jun Cheng   +9 more
doaj   +2 more sources

PD-L1 expression in Xp11.2 translocation renal cell carcinoma: Indicator of tumor aggressiveness [PDF]

open access: yesScientific Reports, 2017
Programmed death ligand-1 (PD-L1), a promising antitumor target, has proven clinical value against many malignancies. However, the PD-L1 content of Xp11.2 translocation renal cell carcinoma (Xp11.2 RCC) and its correlation with clinical outcomes remain ...
Kun Chang   +10 more
doaj   +2 more sources

Robot-assisted partial nephrectomy for TFE3-rearranged renal cell carcinoma: a case report and literature review [PDF]

open access: yesFrontiers in Oncology
BackgroundTFE3-rearranged renal cell carcinoma (TFE3-RCC) is a rare RCC subtype driven by translocation involving Xp11.2 and TFE3 gene fusion. The management of TFE3-RCC is similar to that of other RCC subtypes and primarily involves surgical resection ...
Biao Jiang   +3 more
doaj   +2 more sources

Clinicopathologic, treatment and prognosis study of 46 Xp11.2 translocation/TFE3 gene fusion renal cell carcinomas

open access: yesBMC Urology, 2022
Purpose To report the clinicopathological features and mid- to long-term oncologic results of Xp11.2 translocation/transcription factor E3 (TFE3) gene fusion renal cell carcinomas (Xp11.2 translocation RCCs) in a single large-volume centrecentre. Methods
Jiale Zhou   +5 more
doaj   +1 more source

MiT family translocation renal cell carcinoma with retroperitoneal metastasis in childhood: a case report

open access: yesFrontiers in Pediatrics, 2023
RCC accounts for only 0.1%–0.3% of all kidney tumors and 2%–6% of malignant kidney tumors in children. Accounting for approximately one-third of the total number of cases in children and adolescents with RCC, Xp11.2 tRCC is the most common subtype of the
Kaihang Yang   +3 more
doaj   +1 more source

Renal cell carcinoma in the contralateral kidney with TFE3 gene translocation following chemotherapy for childhood nephroblastoma: A case report and literature review

open access: yesClinical Case Reports, Volume 11, Issue 11, November 2023., 2023
Key Clinical Message Renal cell carcinoma as a secondary malignant neoplasm is relatively rare; however, the possibility of secondary renal cell carcinoma following chemoradiotherapy for childhood nephroblastoma should be considered. Abstract The occurrence of secondary renal cell carcinoma (RCC) following chemoradiotherapy for nephroblastoma is ...
Shunsuke Fujisawa   +8 more
wiley   +1 more source

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