Results 31 to 40 of about 157,061 (320)

Evaluation of Atropine-Xylazine as a Sedative in Buffalo Calves (Bubalus bubalis)

open access: yesItalian Journal of Animal Science, 2010
Twelve experimental trials were undertaken on clinically healthy male buffalo calves. Atropine was administered @ 0.04 mg/kg, IM and xylazine was administered @ 0.04 mg/kg, IM.
S. Singh   +4 more
doaj   +1 more source

Xylazine-associated Wounds: Clinical Experience From a Low-barrier Wound Care Clinic in Philadelphia

open access: yesJournal of addiction medicine, 2023
The veterinary sedative xylazine is spreading in unregulated opioid supplies across North America. Among people who use drugs with repeated exposure to xylazine, a distinct wound type has emerged.
Rachel McFadden   +6 more
semanticscholar   +1 more source

Glutamate-mediated blood-brain barrier opening. implications for neuroprotection and drug delivery [PDF]

open access: yes, 2016
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed ...
CECCANTI , MARCO   +18 more
core   +1 more source

Self-reported Xylazine Experiences: A Mixed Methods Study of Reddit Subscribers

open access: yesmedRxiv, 2023
Objectives: Xylazine is an alpha-2 agonist increasingly prevalent in the illicit drug supply. Our objectives were to curate information about xylazine through social media from People Who Use Drugs (PWUDs). Specifically, we sought to answer the following:
A. Spadaro   +6 more
semanticscholar   +2 more sources

Longitudinal Optogenetic Motor Mapping Revealed Structural and Functional Impairments and Enhanced Corticorubral Projection after Contusive Spinal Cord Injury in Mice [PDF]

open access: yes, 2019
Current evaluation of impairment and repair after spinal cord injury (SCI) is largely dependent on behavioral assessment and histological analysis of injured tissue and pathways. Here, we evaluated whether transcranial optogenetic mapping of motor cortex
Chai, Zhi   +5 more
core   +1 more source

Widespread Distribution of Xylazine Detected Throughout the United States in Healthcare Patient Samples

open access: yesJournal of addiction medicine, 2023
Objectives Xylazine is a tranquilizer commonly added into the illicit drug supply and a likely contributor to overdoses because it does not respond to naloxone reversal. The objective of this study was to perform a retrospective data analysis on xylazine-
A. Holt   +4 more
semanticscholar   +1 more source

Increasing presence of xylazine in heroin and/or fentanyl deaths, Philadelphia, Pennsylvania, 2010–2019

open access: yesInjury Prevention, 2021
Reports from active drug users state that xylazine, the veterinary tranquilliser, has been increasing in the illicit drug supply in Philadelphia. To describe trends and characteristics of unintentional deaths from heroin and/or fentanyl overdose with ...
Jewell Johnson   +3 more
semanticscholar   +1 more source

Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]

open access: yes, 2012
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli   +10 more
core   +5 more sources

Xylazine in Overdose Deaths and Forensic Drug Reports in US States, 2019-2022

open access: yesJAMA Network Open
Key Points Question To what extent is xylazine reported in fatal overdoses and law enforcement drug submissions in different states? Findings In this cross-sectional study of US overdose deaths and forensic reports, 16 states had no xylazine forensic ...
Manuel Cano   +2 more
semanticscholar   +1 more source

The New Stealth Drug on the Street: A Narrative Review of Xylazine as a Street Drug

open access: yesCureus, 2023
Xylazine is an alpha-adrenergic receptor agonist approved for use only in animals with a prescription from a veterinarian. It is a powerful sedative that is slowly infiltrating the recreational street drug scene and is often used by polysubstance abusers.
Joseph V. Pergolizzi Jr.   +5 more
semanticscholar   +1 more source

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