Results 141 to 150 of about 57,211 (287)

Oral Treatment With Heat Shock Protein 65‐Producing Lactococcus lactis Induces Regulatory T Cells, Modulating Inflammatory Response in Leishmania braziliensis Infection

open access: yesImmunology, EarlyView.
Oral treatment with HSP65‐producing Lactococcus lactis after Leishmania braziliensis infection modulates inflammation by promoting lesion resolution through increased IL‐10 production and expansion of regulatory T cells. These findings highlight the potential of oral tolerance induction as a promising therapeutic strategy for chronic inflammatory ...
Camila Mattos Andrade   +11 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

Bacterial fitness for plant colonization is influenced by plant growth substrate

open access: yesNew Phytologist, EarlyView.
Summary Despite advances in our understanding of bacterial plant colonization, the extent to which growth substrate influences the molecular mechanisms enabling bacteria to efficiently colonize plants remains poorly understood. To address this, we used randomly barcoded transposon mutagenesis sequencing (RB‐TnSeq) in Paraburkholderia graminis OAS925 ...
Marta Torres   +6 more
wiley   +1 more source

Highly efficient transgene‐free ErCas12a RNP‐protoplast genome editing and single‐cell regeneration in Nicotiana benthamiana for glyco‐engineering

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana serves as a unique platform for biopharmaceutical production, offering advantages such as efficient and scalable protein synthesis. In addition, custom N‐glycans can be engineered on biopharmaceutical glycoproteins. Yet, plant‐native glycosyltransferases and glycoside hydrolases need to be removed to prevent undesired ...
Lukas C. Blumberg   +8 more
wiley   +1 more source

LARGE1 processively polymerizes length-controlled matriglycan on prodystroglycan. [PDF]

open access: yesNat Commun
Joseph S   +11 more
europepmc   +1 more source

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