Results 151 to 160 of about 45,599 (268)

Dual Role of MtHAC‐1 in Regulating Cellulase and Xylanase Production in Myceliophthora thermophila

open access: yesMicrobial Biotechnology, Volume 18, Issue 8, August 2025.
Through a combination of gene deletion, overexpression analyses, and electrophoretic mobility shift assays, we demonstrate that MtHac‐1 acts as a dual‐function regulator of cellulase and xylanase production, directly modulating the expression of major cellulase and xylanase genes, as well as the regulatory gene Mtxyr1, through promoter binding ...
Yapeng Lai   +4 more
wiley   +1 more source

Engineering of 1,4‐Butanediol and Adipic Acid Metabolism in Pseudomonas taiwanensis for Upcycling to Aromatic Compounds

open access: yesMicrobial Biotechnology, Volume 18, Issue 8, August 2025.
Growth of an aromatics‐overproducing Pseudomonas taiwanensis on adipate and 1,4‐butanediol was engineered for bio‐upcycling. Adaptive laboratory evolution followed by genome sequencing was used to identify and reverse engineer growth‐enabling mutations.
Leonie Op de Hipt   +5 more
wiley   +1 more source

Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose

open access: yesNature Communications
To broaden the substrate scope of microbial cell factories towards renewable substrates, rational genetic interventions are often combined with adaptive laboratory evolution (ALE).
Pavel Dvořák   +11 more
doaj   +1 more source

Xylose utilization promotes Salmonella replication within macrophages and systemic infection in mice

open access: yesVirulence
The intracellular pathogen Salmonella can cause systemic diseases via its survival and replication in host macrophages. Xylose is the second most abundant sugar in nature and Salmonella can use xylose as its sole carbon source for growth.
Xinyue Wang   +6 more
doaj   +1 more source

Optimisation of Laccase Activity From Bacillus atrophaeus Using Response Surface Methodology: A Proof‐Of‐Concept Dye Decolourisation Study

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 4, August 2025.
Summarising the optimisation of laccase production from Bacillus atrophaeus using response surface methodology (RSM) and its application in dye decolourisation. Created with BioRender.com. ABSTRACT This study investigates the enhancement of laccase activity, a copper‐containing enzyme involved in oxidative biodegradation.
Kubra Kocak   +3 more
wiley   +1 more source

Engineering Methylotrophic Yeasts as Cell Factories for Chemical Production Using Methanol as a Feedstock

open access: yesGCB Bioenergy, Volume 17, Issue 8, August 2025.
Methanol, a sustainable and abundant one‐carbon feedstock, can be utilized by natural methylotrophic yeasts to synthesize valuable chemicals. However, methanol‐based manufacturing with these yeasts faces several challenges, including low assimilation efficiency, carbon loss, and methanol toxicity. This review summarizes and discusses recent engineering
Shuxian Wang   +4 more
wiley   +1 more source

Metabolic and Bioprocess Engineering of Clostridium tyrobutyricum for Butyl Butyrate Production on Xylose and Shrimp Shell Waste

open access: yesFoods
Microbial conversion of agri-food waste to valuable compounds offers a sustainable route to develop the bioeconomy and contribute to sustainable biorefinery.
Hao Wang   +7 more
doaj   +1 more source

Two Subunits of the Rpd3 Histone Deacetylase Complex of Cochliobolus heterostrophus Are Essential for Nitrosative Stress Response and Virulence, and Interact With Stress‐Response Regulators ChHog1 and ChCrz1

open access: yesMolecular Plant Pathology, Volume 26, Issue 8, August 2025.
ChPho23 and ChSds3, two components of the Rpd3 histone deacetylase complex associated with ChHog1, regulate the transcription factor ChCrz1 and modulate the nitrosative stress response and virulence in Cochliobolus heterostrophus. ABSTRACT Southern corn leaf blight (SCLB), caused by Cochliobolus heterostrophus, is a destructive disease in maize‐growing
Jinyu Fan   +7 more
wiley   +1 more source

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