Results 21 to 30 of about 58,968 (247)

Does Plant Size Influence Leaf Elements in an Arborescent Cycad?

Biology, 2018
Plant size influences the leaf nutrient relations of many species, but no cycad species has been studied in this regard. We used the arborescent Cycas micronesica K.D.
Thomas E. Marler, Murukesan V. Krishnapillai   +1 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Doğu Anadolu Bölgesinde Güvenilir Yağışın Belirlenmesi

Journal of Agricultural Sciences, 1997
Bu çal ışmada Doğu Anadolu Bölgesinde Ağrı , Bingöl, Elazığ , Erzincan, Erzurum, Iğd ı r, Kars, Malatya, Muş ve Tunceli illeri ile bu illere bağl ı 106 meteoroloji istasyonundan elde edilen verilere göre, güvenilir ya ğış değerlerinin elde edilmesine ...
Türker Türker, M.ali Tokgöz
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Ankara Murted Sulamasında Su Kullanım ve Dağıtım Etkinliğinin Belirlenmesi

Journal of Agricultural Sciences, 1997
Bu çal ışmada, Devlet Su I şleri taraf ı ndan 1971 y ı l ı nda işletmeye aç ı lan Mürted sulama projesi ele al ı nmış ve ovan ı n sulamas ı için yapı lan tesislerden optimum biçimde yararlanmaya ili şkin seçeneklerin araşt ı rı lmas ı planlanmıştı r. Bu
Nurinisa Ağlamış, M.ali Tokgoz
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Eskişehir Sulaması Sağ Sahil Sulama Alanında Sistem Performansının Değerlendirilmesi

Journal of Agricultural Sciences, 1998
Bu çal ışma Eskişehir Sulamas ı n ı n 1994 y ı l ı na iliş kin sulama sistem performans ı n ı n değ erlendirilmesi amac ı yla yap ı lm ışt ı r. Eskişehir Sağ Sahil Sulamas ı araşt ı rma alan ı olarak seçilmi ştir.
Boğaçhan Benli, Mevlüt Beyrıbey
doaj   +1 more source

Enigma proteins regulate YAP mechanotransduction [PDF]

Journal of Cell Science, 2018
ABSTRACT Human cells can sense mechanical stress acting upon integrin adhesions and respond by sending the YAP (also known as YAP1) and TAZ (also known as WWTR1) transcriptional co-activators to the nucleus to drive TEAD-dependent transcription of target genes. How integrin signaling activates YAP remains unclear.
Ahmed Elbediwy, Hannah Vanyai, Maria-del-Carmen Diaz-de-la-Loza, David Frith, Ambrosius P. Snijders, Barry J. Thompson   +5 more
openaire   +3 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source