Results 111 to 120 of about 6,571 (196)

Multi-omic analyses of m5C readers reveal their characteristics and immunotherapeutic proficiency

open access: yesScientific Reports
5-methylcytosine (m5C) is a post-transcriptional RNA modification identified, m5C readers can specifically identify and bind to m5C. ALYREF and YBX1 as members of m5C readers that have garnered increasing attention in cancer research.
Rui Xu, Yue Wang, Ye Kuang
doaj   +1 more source

MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer

open access: yesCancer Biology & Medicine
Objective: Identifying biomarkers that predict the efficacy and prognosis of chemoradiotherapy is important for individualized clinical treatment. We previously reported that high murine double minute 1 (MDM1) expression in patients with rectal cancer is
Ningxin Ren   +11 more
doaj   +1 more source

The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis

open access: yesJournal of Translational Medicine
Cervical cancer progresses through distinct precancerous stages, making early screening and intervention crucial for prevention. However, conventional screening modalities, such as cytology and HPV testing, face challenges related to sensitivity, specificity, and resource dependency.
Lu Zhao   +11 more
openaire   +3 more sources

5-methylcytosine regulated CCNL2 promotes tumorigenesis and cisplatin resistance of ovarian cancer with therapeutic implications

open access: yesJournal of Ovarian Research
Backgroud Ovarian cancer (OC) is the most lethal gynecological tumor, primarily due to resistance to chemotherapy. Cyclin L2 (CCNL2) is a novel member of the cyclin family and mainly localized in nucleus.
Kai Zhang   +5 more
doaj   +1 more source

TAGLN2 induces resistance signature ISGs by activating AKT-YBX1 signal with dual pathways and mediates the IFN-related DNA damage resistance in gastric cancer

open access: yesCell Death and Disease
Recently, various cancer types have been identified to express a distinct subset of Interferon-stimulated genes (ISGs) that mediate therapy resistance.
Huiqin Zhuo   +7 more
doaj   +1 more source

Additional file 3: of The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-ÎşB signaling axis

open access: yes, 2019
Figure S3. Correlation between the expression of YBX1, G3BP1 and SPP1 from LinkedOmics database. (A) YBX1 was positively correlated with G3BP1. (B) G3BP1 was positively correlated with SPP1.
Yuanjie Niu (214916)   +11 more
core   +1 more source

PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes

open access: yesCell Communication and Signaling
Timely and accurate translation of maternal mRNA is essential for oocyte maturation and early embryonic development. Previous studies have highlighted the importance of Primordial Germ cell 7 (PGC7) as a maternal factor in maintaining DNA methylation of ...
Yingxiang Liu   +7 more
doaj   +1 more source

YBX1 oncogene amplification and over-expression in breast cancer

open access: yes, 2015
Full text is available to authenticated members of The University of Auckland only.Breast cancer is a common diagnosis, however prognosis remains poor for certain subsets of patients and further understanding of breast cancer biology is sorely needed to ...
Jebb, Abbey
core  

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