Results 171 to 180 of about 1,258,398 (362)
Advanced Science, EarlyView.By combining snRNA‐seq and bulk RNA‐seq, this study identified key hepatocyte subtypes, genes, and pathways in HCC. It established a Quantile Distribution Model, providing potential targets for HCC diagnosis and treatment. It categorized HCC into metabolic, inflammatory, and matrix classes, each with sensitive drugs identified.
Huanhou Su +18 more
wiley +1 more source
Demonstrating the Use of a Fungal Synthesized Quinone in a Redox Flow Battery
Batteries &Supercaps, Volume 6, Issue 1, January 2023., 2023 Biobased: The filamentous fungus can be used as an environmentally and sustainable benign source to produce the bio‐based quinone phoenicin. This natural compound shows electrochemical properties, which can be used as the active material in the negative electrolyte in a redox flow battery with results showing that biologically produced quinones may ...
Charlotte Overgaard Wilhelmsen +15 more
wiley +1 more source
On the structure of proten-protein interaction networks [PDF]
arXiv, 2003 We present a simple model for the underlying structure of protein-protein pairwise interaction graphs that is based on the way in which proteins attach to each other in experiments such as yeast two-hybrid assays. We show that data on the interactions of human proteins lend support to this model.
arxiv
The Yeast Flora of Bottled Ciders [PDF]
, 1908 Elsie B. Pearce, B. T. P. Barker
openalex +1 more source
Unwrapping the Ciliary Coat: High‐Resolution Structure and Function of the Ciliary Glycocalyx
Advanced Science, EarlyView.The ciliary membrane is decorated in glycosylated proteins that define the interaction of the cilium with its environment. The main component of the ciliary coat of the green alga Chlamydomonas reinhardtii, FMG1, is characterized by cryo‐electron microscopy, proteomics, and live cell microscopy with flow‐based adhesion assays.
Lara M. Hoepfner +8 more
wiley +1 more source
Advanced Science, EarlyView.This study elucidates the mechanism underlying LINC01235 promotes clonal evolution and selection under treatment pressure by facilitating DNA replication licensing and CIN, leading to increased therapeutic resistance in HER2+ breast cancer. Targeting LINC01235‐related pathways with ATR inhibitors may be a viable strategy for clinical application ...
Qi Zhang +18 more
wiley +1 more source
Mapping the Beta-Sheet Structure of the Yeast Prion Sup35 through Creation of Targeted Mutant Forms [PDF]
, 2013 Proteins with an aggregated form rich in beta-sheet structure are known as amyloids, of which a subset are infectious. These infectious proteins are known as prions and cause diseases including bovine spongiform encephalopathy (“Mad Cow” disease ...
Davis, Emily K. +2 more
core +1 more source
Advanced Science, EarlyView.Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley +1 more source