Results 181 to 190 of about 1,258,398 (362)
Beyond the GTP‐cap: Elucidating the molecular mechanisms of microtubule catastrophe
BioEssays, Volume 45, Issue 1, January 2023., 2023 Microtubule dynamics are essential for myriad cellular processes. The switching between microtubule growth and shrinkage is traditionally explained by the loss of a protective “cap” of GTP‐bound tubulin subunits from the growing microtubule end. New research shows that features beyond the nucleotide content at the growing end impact microtubule ...
Veronica J. Farmer, Marija Zanic
wiley +1 more source
Targeted Mutagenesis of the Oligopeptide Repeat Domain of the Yeast Prion Sup35 [PDF]
, 2014 The formation of prions in the baker’s yeast Saccharomyces cerevisiae is determined by amino acid composition rather than the primary sequence of amino acids.
Davis, Emily, Knox, James D.
core +1 more source
Advanced Science, EarlyView.An automated tool incorporating a large language model (LLM) streamlines the extraction and classification of protein expression and purification methods from 64 909 PDB‐associated articles. By identifying trends in buffer components, fusion tags, expression conditions, and crosslinker/detergent preferences, the tool provides valuable insights into the
Zhuojian Chen, J. Sivaraman
wiley +1 more source
A Model of Epigenetic Inheritance Accounts for Unexpected Adaptation to Unforeseen Challenges
Advanced Science, EarlyView.A general model of inheriting changes that are acquired during the lifetime of individuals demonstrates tremendous benefits to the population, including escape from extinction in changing environments. Contrasting the model with experimental data shows that inheritance of acquired changes enables rapid adaptation to unforeseen challenges, and accounts ...
Dino Osmanović +2 more
wiley +1 more source
Biotechnology Journal, Volume 18, Issue 1, January 2023., 2023 Graphical Abstract and Lay Summary The heterogenous production conditions in large‐scale bioreactors cause scale‐up problems, such as reduced biomass or product yield, to occur during bioprocesses. In this study, we designed a two‐compartment scale‐down reactor and used it to simulate large‐scale heterogenous production conditions, allowing us to ...
Florian Mayer +7 more
wiley +1 more source
The addition of yeast to a milk diet [PDF]
, 1921 P. B. Hawk, C. A. Smith, Olaf Bergeim
openalex +1 more source
Advanced Science, EarlyView.The target of rapamycin (TOR) complex is a central plant growth regulator. Here, the protein–protein interactions underlying its various functions are mapped by pupylation‐based proximity‐labeling in Arabidopsis, using TOR complex subunits LST8‐1 and RAPTOR1, alongside TOR inhibitor FK506‐binding protein, as baits.
Shuai Zheng +9 more
wiley +1 more source
Control of Rhizobia Endosymbiosis by Coupling ER Expansion with Enhanced UPR
Advanced Science, EarlyView.This study reconstructs legume nodule symbiotic cells using three‐dimensional (3D) scanning electron microscopy (SEM) and uncovers that endoplasmic reticulum (ER) expansion and activation of the unfolded protein response (UPR) are two key events in rhizobia accommodation.
Jing Ren +8 more
wiley +1 more source