Results 181 to 190 of about 1,406,804 (289)
Slm9, a Novel Nuclear Protein Involved in Mitotic Control in Fission Yeast [PDF]
Junko Kanoh, Paul Russell
openalex +1 more source
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen +12 more
wiley +1 more source
Yeast Species Associated with Industrial Cultures of the Marine Microalgae <i>Tisochrysis lutea</i>: Temperature Profiles and Auxin Production. [PDF]
Matos M +6 more
europepmc +1 more source
The Yeast RNA Polymerase II-associated Factor Iwr1p Is Involved in the Basal and Regulated Transcription of Specific Genes [PDF]
Lorena Peiró-Chova, Francisco Estruch
openalex +1 more source
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang +11 more
wiley +1 more source
Diversity of Yeast and Drosophila Species Associated with Grape Sour Rot in China. [PDF]
Han J +6 more
europepmc +1 more source
Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley +1 more source
Revealing Non-Conventional and Thermotolerant Yeasts from Tropical Regions: Diversity and Potential Traits for Bioproducts. [PDF]
Nurcholis M +5 more
europepmc +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source

