Results 241 to 250 of about 367,897 (354)

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

open access: yesAdvanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao   +10 more
wiley   +1 more source

Development of experimental sporothrichosis in a murine model with yeast and mycelial forms of Sporothrix schenkii

open access: diamond, 2018
Márcia de Oliveira Nobre   +7 more
openalex   +2 more sources

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

open access: yesAdvanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao   +12 more
wiley   +1 more source

Yeast and Yeast Storage [PDF]

open access: yesJournal of the Institute of Brewing, 1924
openaire   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

open access: yesAdvanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song   +14 more
wiley   +1 more source

The Brief Case: Yeast, chlamydospores, and hyphae—a case of disseminated mucormycosis

open access: green
Nicole E. Putnam   +7 more
openalex   +2 more sources

Isolation of a fission yeast mutant cell affected in MAP kinase signaling and sterol biosynthesis.

open access: gold, 2009
Kiwamu Imagawa   +5 more
openalex   +1 more source

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