Results 281 to 290 of about 356,347 (342)

Modeling heterogeneity in large‐scale bioreactors using the method of moments with a truncated normal distribution

open access: yesAIChE Journal, EarlyView.
ABSTRACT Large‐scale bioreactors in industrial bioprocesses pose challenges due to extracellular concentration gradients and intracellular heterogeneity. This study introduces a novel approach integrating the method of moments with truncated normal distributions (MM‐TND) to model intracellular heterogeneity while maintaining computational feasibility ...
Ittisak Promma   +3 more
wiley   +1 more source

CoRoFR: Community Detection of Feature Graph Improves Feature Selection Using Robust Fuzzy Rough Set

open access: yesAdvanced Intelligent Systems, EarlyView.
In machine learning, features often function as communities in many tasks, especially in medicine. However, existing feature selection methods struggle to mine feature collaborations, which can boost predictive performance. Moreover, they are noise‐sensitive, leading to suboptimal feature selection and accuracy degradation.
Duanyang Feng   +4 more
wiley   +1 more source

Environmental yeasts differentially impact the development and oviposition behavior of the Asian tiger mosquito Aedes albopictus. [PDF]

open access: yesMicrobiome
Malassigné S   +9 more
europepmc   +1 more source

Pbs2 regulates late‐stage macroautophagy in Saccharomyces cerevisiae

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The MAPK family member Pbs2 and its role in autophagy. Macroautophagy consists of five key steps: the initiation at the pre‐autophagosomal structure (PAS), elongation of the isolation membrane (IM), maturation of the autophagosome, fusion of autophagosomes with vacuoles, and degradation of autophagic bodies.
Jianing Song   +8 more
wiley   +1 more source

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang   +4 more
wiley   +1 more source

Solid‐State NMR Reveals Reorganization of the Aspergillus fumigatus Cell Wall Due to a Host‐Defence Peptide

open access: yesAngewandte Chemie, EarlyView.
Understanding the mode of action is critical to develop new antifungal drugs. Solid‐state NMR was used to study the reorganization of the Aspergillus fumigatus cell wall by a host‐defence peptide. We identified specific polysaccharides and amino acids that are affected by the peptide.
Ajit Kumar Bishoyi   +5 more
wiley   +1 more source

A Genetically Encoded Homocysteine Precursor to Probe Protein Active Sites and to Addict Escherichia coli to a Noncanonical Amino Acid Directly Involved in Catalysis

open access: yesAngewandte Chemie, EarlyView.
A new genetically encoded amino acid is chemically converted into homocysteine (Hcy) under mild conditions to probe and to activate protein active sites. Surprisingly, Hcy can replace cysteine or serine residues in several enzymes. Its potential for a widespread use in proteins is further underlined by rendering Escherichia coli dependent on Hcy ...
Clara Dunker, Henning D. Mootz
wiley   +1 more source

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