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Yersinia pestis belongs to those pathogenic bacteria which produce lipopolysaccharide (LPS) having the function of a toxin. In order to make a toxic effect the polymer must be separated from the cell outer membrane and presented to the immunocompetent ...
V. I. Tynyanova+3 more
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Plasmids in Yersinia pestis [PDF]
Pesticinogenic and Ca2+-dependent strains of Yersinia pestis harbored plasmids of about 6 and 45 megadaltons, respectively. In addition, most isolates examined possessed a cryptic 65-megadalton plasmid.
D M Ferber, R R Brubaker
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To the Editor: Drancourt et al. (1) report the development of an original genotyping system for Yersinia pestis based on intergenic spacer sequencing. However, the approach appears to rely upon the characterization of polymorphisms due to tandem repeat variation.
Didier Raoult+4 more
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Comme aucune autre maladie, la peste incarne l’image de la mort. Maladie parmi les plus mortifères de l’histoire de l’humanité, fléau biblique, la « mort noire » s’est imposée dans la mémoire et l’imaginaire des peuples comme synonyme de malédiction, bouleversant le paysage économique, démographique, social et peut-être génétique des pays qu’elle a ...
Demeure, Christian, Carniel, Elisabeth
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Hotspots of genetic change in Yersinia pestis. [PDF]
The relative contributions of mutation rate variation, selection, and recombination in shaping genomic variation in bacterial populations remain poorly understood. Here we analyze 3318 Yersinia pestis genomes, spanning nearly a century and including 2336 newly sequenced strains, to shed light on the patterns of genetic diversity and variation ...
Wu Y+14 more
europepmc +4 more sources
Background Accurate identification is necessary to discriminate harmless environmental Yersinia species from the food-borne pathogens Yersinia enterocolitica and Yersinia pseudotuberculosis and from the group A bioterrorism plague agent Yersinia pestis ...
Drancourt Michel+3 more
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Inhibition of Neutrophil Primary Granule Release during
Inhalation of Yersinia pestis causes primary pneumonic plague, the most severe manifestation of plague that is characterized by a dramatic neutrophil influx to the lungs.
Kara R. Eichelberger+2 more
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Yersinia murine toxin (Ymt) is a phospholipase D encoded on a plasmid acquired by Yersinia pestis after its recent divergence from a Yersinia pseudotuberculosis progenitor. Despite its name, Ymt is not required for virulence but acts to enhance bacterial
David M Bland+4 more
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Yersinia pestis Plasminogen Activator
The Gram-negative bacterium Yersinia pestis causes plague, a fatal flea-borne anthropozoonosis, which can progress to aerosol-transmitted pneumonia. Y. pestis overcomes the innate immunity of its host thanks to many pathogenicity factors, including plasminogen activator, Pla.
Florent Sebbane+2 more
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Contribuição para o diagnóstico de peste Contribution towards plague diagnosis
Apesar de sua fundamentação clínico-epidemiológica, numerosos casos suspeitos de peste nos focos brasileiros têm sido descartados por serem negativos pelo teste de hemaglutinação para detecção de anticorpos contra o antígeno F1 da Yersinia pestis.
Alzira Maria Paiva de Almeida+7 more
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