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Oncostatin M regulates macrophages polarization in osseointegration via yes-associated protein
International Immunopharmacology, 2023Oncostatin M(OSM), secreted by monocytes and macrophages, has been noted to participate in bone homeostasis and macrophage polarization, which might be regulated by yes-associated protein (YAP). This study aimed to elucidate the influence and mechanisms of OSM-YAP on macrophages polarization in osseointegration.In vitro, flow cytometry, real-time PCR ...
Ying Yuan +5 more
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Yes-associated protein (YAP) molecule expression in odontogenic epithelium of ameloblastoma
Clinical Oral Investigations, 2018YAP (Yes-associated protein molecule) augments multiple processes known to be important for tumor progression and metastasis. Hence, the application of YAP as a targeted therapy for several malignancies has been documented in the literature. Ameloblastoma being a locally invasive odontogenic lesion causes tissue destruction and presents with a great ...
Rahul Anand +4 more
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Yes‐associated protein 1 promotes the differentiation and mineralization of cementoblast
Journal of Cellular Physiology, 2017Yes‐associated protein 1 (YAP1) transcriptional coactivator is a mediator of mechanosensitive signaling. Cementum, which covers the tooth root surface, continuously senses external mechanical stimulation. Cementoblasts are responsible for the mineralization and maturation of the cementum.
Beining Yang +4 more
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Yes-associated protein 1 regulates the stability of DeltaNp63alpha.
Cell cycle (Georgetown, Tex.), 2010Regulation of DeltaNp63alpha can be achieved at the transcriptional and post-translational levels, with the latter being greatly influenced by external stimuli such as DNA damaging agents. In this present study, we demonstrated that DeltaNp63alpha physical interacts with Yes-associated protein 1 (Yap1).
Aditi, Chatterjee +3 more
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Yes-associated protein signalling in pancreatic cancer microenvironment
European Journal of Cancer, 2016B. Xie +4 more
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The role of Yes-associated protein (YAP) in vertebrate development
2011Yes-associated protein 65 (YAP) contains multiple protein-protein interaction domains and functions as both a transcriptional co-activator and as a scaffolding protein within the cytoplasm or nucleus. Given that YAP binds to so many proteins that are critical for proper embryonic development and that this factor functions as a transcriptional co ...
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