Results 121 to 130 of about 8,550,318 (390)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Meta-analysis of drought and heat stress combination impact on crop yield and yield components.

Physiologia Plantarum : An International Journal for Plant Biology, 2020
Episodes of prolonged drought coupled with heat waves (i.e., drought and heat combination) can have a devastating impact on agricultural production and crop yield.
I. Cohen, Sara I. Zandalinas, Clayton Huck, F. Fritschi, R. Mittler   +4 more
semanticscholar   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Variability behavior of yield stress for unclassified tailings pasted under measurement time‒velocity double factors

工程科学学报, 2020
The rake torque of deep cone thickener, pipeline resistance, and paste accumulation slope were important technological parameters for the efficient paste backfill process, which are to be solved or optimized for the practical application in mines.
Cui-ping LI, Bing-heng YAN, Shao-yong WANG, He-zi HOU, Ge-zhong CHEN   +4 more
doaj   +1 more source

The implementation of the vegter yield criterion and a physically based hardening rule in finite elements [PDF]

, 1998
A new material description for sheet metal forming using Finite Elements has been developed. The description consists of a yield criterion and a hardening rule.
Carleer, B.D., Carleer, B.D., Huetink, Han, Meinders, Vincent T., Pijlman, H.H., Vegter, H.   +5 more
core   +1 more source

Effects of Water Stress on Photosynthesis, Yield, and Water Use Efficiency in Winter Wheat

Water, 2020
Drought has become one of the major constraints to agricultural development, particularly in areas that lack water. Studying the effects of different water stresses on the photosynthesis, growth, yield, water use efficiency (WUE) and irrigation water ...
Wenhui Zhao, Leizhen Liu, Qiu Shen, Jianhua Yang, Xinyi Han, F. Tian, Jianjun Wu   +6 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source