Results 1 to 10 of about 111,326,060 (152)
From osteoblast to osteoclast: new insights of Yin-Yang theory in bone remodeling
World Journal of Traditional Chinese Medicine, 2015 Yin-Yang theory plays critical role in traditional Chinese medicine (TCM) science. However, there are many competing interpretations of Yin-Yang theory in the context with the development in biology, and no consensus has been established.
Dong-Feng Zhao +7 more
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Proviral Silencing in Embryonic Cells Is Regulated by Yin Yang 1
Cell Reports, 2013 Embryonic cells transcriptionally repress the expression of endogenous and exogenous retroelements. Trim28, a key player in this silencing, is known to act in a large DNA-bound complex, but the other components of the complex are not fully characterized.
Sharon Schlesinger +4 more
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The Why of YY1: Mechanisms of Transcriptional Regulation by Yin Yang 1 [PDF]
Frontiers in Cell and Developmental Biology, 2020 First described in 1991, Yin Yang 1 (YY1) is a transcription factor that is ubiquitously expressed throughout mammalian cells. It regulates both transcriptional activation and repression, in a seemingly context-dependent manner.
Thijs C. J. Verheul +3 more
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Frontiers in Pharmacology, 2022 Glioblastoma (GBM) is the most malignant tumor of the central nervous system in adults. Irradiation (IR) and temozolomide (TMZ) play an extremely important role in the treatment of GBM.
Xiao Liu +18 more
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Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis
Advanced Science, 2022 Ferroptosis is a type of programmed cell death caused by disruption of redox homeostasis and is closely linked to amino acid metabolism. Yin Yang 2 (YY2) and its homolog Yin Yang 1 (YY1) are highly homologous, especially in their zinc‐finger domains ...
Yanjun Li +7 more
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The role of transcription factor Yin Yang‐1 in colorectal cancer
Cancer Medicine, 2023 Background Yin Yang‐1 (YY1) is identified as a transcription factor with multiple functions. However, the role of YY1 in tumorigenesis remains controversial and its regulatory effects may depend upon not only cancer types, but also its interacting ...
Zhiying Shao +8 more
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Rac GTPase activating protein 1 promotes the glioma growth by regulating the expression of MCM3
Translational Oncology, 2023 Glioma is the most common tumor of the nervous system. The diffuse growth and proliferation of glioma poses great challenges for its treatment. Here, Transcriptomic analysis revealed that Rac GTPase activating protein 1 (RACGAP1) is highly expressed in ...
Bo Jia +13 more
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Yin Yang 1 impacts upon preeclampsia by regulating Treg/TH17 cells and PI3K/AKT pathway
Journal of Immunotoxicology, 2023 Preeclampsia (PE) is a common obstetric syndrome with an unclear etiology and pathogenesis. The study here aimed to investigate the role of Yin Yang 1 (YY1) in PE, and to reveal any YY1-regulated mechanisms in PE.
Haowen Li +4 more
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Plasma Membrane Calcium ATPase Regulates Stoichiometry of CD4+ T-Cell Compartments
Frontiers in Immunology, 2021 Immune responses involve mobilization of T cells within naïve and memory compartments. Tightly regulated Ca2+ levels are essential for balanced immune outcomes. How Ca2+ contributes to regulating compartment stoichiometry is unknown.
Maylin Merino-Wong +2 more
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Traditional Chinese Medicine Factors Associated with Diabetic Nephropathy Diagnosed by Renal Biopsy [PDF]
Zhongguo quanke yixueBackground Diabetic nephropathy (DN) is the common microvascular complication of diabetes mellitus, and also one of the main causes of end-stage renal disease. Renal biopsy is the gold standard for the pathological diagnosis of DN.
ZHANG Ruimin, DONG Zheyi, LI Shuang, WANG Qian, CHEN Xiangmei
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