Results 11 to 20 of about 111,326,060 (152)
Yin Yang 1: Role in Leishmaniasis
CellsLeishmaniasis, caused by protozoan parasites of the genus Leishmania, is one of the most neglected human diseases, affecting millions worldwide. A detailed understanding of the molecular mechanisms that govern the outcome of macrophage–Leishmania ...
Devki Nandan +2 more
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The yin, the yang, and the Angiopoietin-1 [PDF]
Journal of Clinical Investigation, 2011 Twenty years after the discovery of the vascular endothelial Tie receptor tyrosine kinases and 15 years after the discovery of the Tie2 ligand, angiopoietin-1 (Angpt1, also known as Ang1), a study published in the current issue of the JCI reveals an unexpected loss-of-function phenotype of mice conditionally deleted of the Angpt1 gene.
Alitalo Kari +3 more
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, 2023 Image of a sculpture by Penny Hardy entitled Yin and Yang (2013) illustrating our different ...
Hardy, Penny, Penny Hardy
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The Oncogenic Role of Yin Yang 1 [PDF]
Critical Reviews− in Oncogenesis, 2011 Yin Yang 1 (YY1) is a transcription factor with diverse and complex biological functions. YY1 either activates or represses gene transcription, depending on the stimuli received by the cells and its association with other cellular factors. Since its discovery, a biological role for YY1 in tumor development and progression has been suggested because of ...
Qiang, Zhang +3 more
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Transcription, 2010 As a transcription factor, Yin Yang 1 (YY1) regulates the transcription of a dazzling list of genes and the number of its targets still mounts. Recent studies revealed that YY1 possesses functions independent of its DNA binding activity and its regulatory role in tumorigenesis has started to emerge.
Zhiyong, Deng +3 more
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Regulation of Yin Yang 1 by Tyrosine Phosphorylation [PDF]
Journal of Biological Chemistry, 2015 Yin Yang 1 (YY1) is a member of the GLI-Krüppel class of DNA and RNA binding transcription factors that can either activate or repress gene expression during cell growth, differentiation, and embryogenesis. Although much is known about YY1 interacting proteins and the target promoters regulated by YY1, much less is known about YY1 regulation through ...
Gary Z, Wang, Stephen P, Goff
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The Information Philosophy Implication of Yin-Yang
, 2023 Yin-yang, thought in ancient Chinese philosophy, contains rich information philosophy implications. The theory of “Yin-yang Gan Sheng” believes that Yin and Yang’s interaction can make emergences of new things and new life, which ...
Huimin Zhang
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, 2016 A system which consisted of multidimensional liquid chromatography (Yin-yang MDLC) coupled with mass spectrometry was used for the identification of peptides and phosphopeptides.
Chia-Hui Shieh (2399971) +5 more
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Yin Yang 1 expression in human tumors [PDF]
Cell Cycle, 2010 The Yin Yang 1 (YY1) transcription factor has been identified to target a plethora of potential target genes, the products of which are important for proliferation and differentiation. The mechanisms of YY1 action are related to its ability to initiate, activate or repress transcription depending on the context in which it binds.
Apostolos, Zaravinos +1 more
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Yin Yang 1 Is a Negative Regulator of p53 [PDF]
Cell, 2004 Yin Yang 1 (YY1) is a transcription factor that plays an essential role in development. However, the full spectrum of YY1's functions and mechanism of action remains unclear. We find that YY1 ablation results in p53 accumulation due to a reduction of p53 ubiquitination in vivo.
Sui, Guangchao +10 more
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