Results 131 to 140 of about 8,254 (185)

Synthesis of (±)-zearalenone

Tetrahedron, 1987
The aliphatic portion of (±)-zearalenone has been synthesised by a new simple route starting from 2,3-dihydropyran and 2-acetyl-γ-butyrolactone by employing dithiane for C-C bond formation. The final condensation of this segment with the aromatic part and subseqnet transformations led to (±)-zearalenone.
A.V. Rama Rao, M.N. Deshmukh, G.V.M. Sharma   +2 more
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Zearalenon in Lebensmitteln

Mycotoxin Research, 2005
Im Rahmen eines Fusarienforschungvorhabens wurden Analyseverfahren fur Zearalenon auf der Basis von ELISA, HPLC-FLD und LC-MS/MS MS/MS validiert. Bislang wurden 4556 Lebensmittel auf den Gehalt an Zearalenon untersucht. 84% der Maismehle und 53% Maisgriese weisen eine mittlere und 95 Maiskeimol eine hohe Zearalenonbelastung auf.
O. Kappenstein, A. Brockmeyer, R. Dietrich, V. Curtui, H. Klaffke, J. Lepschy, E. Märtlbauer, E. Schneider, C. Seidler, G. Thielert, E. Uslenber, R. Weber, J. Wolff   +12 more
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Effects of Processing on Zearalenone

2002
Zearalenone (ZEN), a common contaminant of all major cereal grains worldwide, is produced by some plant pathogenic molds including Fusarium graminearum and F. culmorum. The biological activity of this mycotoxin is mainly attributed to its estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.
Dojin, Ryu, Lauren S, Jackson, Lloyd B, Bullerman   +2 more
openaire   +2 more sources

Occurrence of zearalenone in maize

Mycotoxin Research, 1993
The occurrence of zearalenone in whole plants and parts of maize usually used for silage making was investigated during the cultivation period of the crop.Zearalenone was detected upto several hundreds of μg/kg DM, that mainly accumulated at the end of the ripening process thus contaminating the silages subsequently.
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Allyl Derivatives of Zearalenone

Journal of Pharmaceutical Sciences, 1980
The Claisen rearrangement of 4-O-allylzearalenone led to only one principal product, which was identified as 3-allylzearalenone with the aid of photochemical isomerization and PMR spectroscopy. This general method is useful for distinguishing 3-substituted zearalenone isomers from 5-substituted isomers.
openaire   +2 more sources

Investigations on metabolism of zearalenone in broilers

Mycotoxin Research, 2000
Two experiments were carried out with male broilers to examine excretion kinetics of zearalenone (ZEA) and its metabolites (Exp. 1) and their occurrence in blood plasma and bile fluid (Exp.2) after a single oral dose of ZEA (approximately 6 µg/kg body weight) from naturally contaminated wheat.
S, Dänicke, K H, Ueberschär, I, Halle, H, Valenta   +3 more
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Metabolism of zearalenone by Fusarium Roseum

Journal of Toxicology and Environmental Health, 1977
Twenty products associated with the metabolism of zearalenone by Fusarium roseum were analyzed with respect to time and culture conditions. By statistical analysis a set of six metabolites possibly related to zearalenone were selected. These products were characterized by gas chromatography--mass spectrometry and other methods.
J A, Steele, C J, Mirocha, S V, Pathre
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Determination of zearalenone and ochratoxin A in soil

Analytical and Bioanalytical Chemistry, 2003
Mycotoxins are secondary metabolites, formed by the action of fungi on agricultural crops in the field or during storage. These metabolites are highly toxic to animals and humans and high levels have been measured in agricultural crops. In order to evaluate human risks due to ingestion of mycotoxin-contaminated food different methods have been ...
Mortensen, G. K., Strobel, B. W., Hansen, H. C. B.   +2 more
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Physiologically Based Pharmacokinetics of Zearalenone

Journal of Toxicology and Environmental Health, Part A, 2009
The objectives of this study were to (1) develop physiologically based pharmacokinetic (PBPK) models for zearalenone following intravenous (i.v.) and oral (p.o.) dosing in rats and (2) predict concentrations in humans via interspecies scaling. The model for i.v.
Beom Soo, Shin, Seok Hyun, Hong, Jürgen B, Bulitta, Jong Bong, Lee, Sang Wook, Hwang, Hyoung Jun, Kim, Seung Du, Yang, Hae-Seong, Yoon, Do Jung, Kim, Byung Mu, Lee, Sun Dong, Yoo   +10 more
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Metabolism of Zearalenone in Rat Liver

Acta Pharmacologica et Toxicologica, 1978
Abstract The metabolism of zearalenone in rat liver has been investigated. The studies were performed mainly with liver homogenate, though isolated microsomes and hepatocytes have also been used. Zearalenone was metabolized along two principal pathways, conjugation with glucuronic acid, which was the main route and reduction to an isomer of zearalenol.
K H, Kiessling, H, Pettersson
openaire   +2 more sources