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Estrogenicity of novel phase I and phase II metabolites of zearalenone and cis-zearalenone
Toxicon, 2015 Zearalenone and its cis-isomer, cis-zearalenone, are nonsteroidal mycotoxins that elicit an estrogenic response upon binding to the estrogen receptor.
Martin Penkert +2 more
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Transformation of zearalenone to zearalenone-sulfate by Aspergillus spp.
World Mycotoxin Journal, 2010The primary goal of this research was to assess the biotransformation of zearalenone (ZEA), an oestrogenic mycotoxin, into ZEA-sulfate by some Aspergillus section Nigri isolates. A. niger isolates were shown to be able to convert ZEA after 72 h of incubation at different ZEA concentrations (5 to 150 µg/ml).
G. Jard +6 more
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Zearalenone production in barley
Annals of Applied Biology, 1975SUMMARY A plot of barley cv. Golden Promise was sprayed with an isolate of Fusarium culmorum known to produce zearalenone, an oestrogenic toxin. The grain was harvested and stored under conditions that were known to induce toxin production in sterilized grain inoculated with the same strain. Toxin was not found in the harvested grain but appeared 20
V J, Gross, J, Robb
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Microbial cleavage of zearalenone
Xenobiotica, 19881. Zearalenone, a fungal oestrogenic compound, was subjected to microbial transformation studies. Preliminary screening with 150 fungal species showed that Gliocladium roseum was capable of metabolizing zearalenone in 80-90% yields. 2. Large-scale fermentation with G. roseum produced a 1:1 mixture of 1-(3,5-dihydroxyphenyl)-10'-hydroxy-1-undecen-6'-one
S, el-Sharkawy, Y J, Abul-Hajj
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Urinary zearalenone measured with ELISA as a biomarker of zearalenone exposure in pigs
Mycotoxin Research, 2014The suitability to assess zearalenone (ZEA) exposure in pigs of a commercial ELISA kit for ZEA analysis in urine was tested. A daily dose of 0, 5, 10, 20 and 40 μg synthetic ZEA per kilogram BW was administered via the feed to four gilts per dose group, and after 3 and after 7 days of ZEA intake, urine samples were assayed with the ELISA which has a ...
Gutzwiller A, Gafner JL, Silacci P
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Mycotoxin Research, 2005
Im Rahmen eines Fusarienforschungvorhabens wurden Analyseverfahren fur Zearalenon auf der Basis von ELISA, HPLC-FLD und LC-MS/MS MS/MS validiert. Bislang wurden 4556 Lebensmittel auf den Gehalt an Zearalenon untersucht. 84% der Maismehle und 53% Maisgriese weisen eine mittlere und 95 Maiskeimol eine hohe Zearalenonbelastung auf.
O. Kappenstein +12 more
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Im Rahmen eines Fusarienforschungvorhabens wurden Analyseverfahren fur Zearalenon auf der Basis von ELISA, HPLC-FLD und LC-MS/MS MS/MS validiert. Bislang wurden 4556 Lebensmittel auf den Gehalt an Zearalenon untersucht. 84% der Maismehle und 53% Maisgriese weisen eine mittlere und 95 Maiskeimol eine hohe Zearalenonbelastung auf.
O. Kappenstein +12 more
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Effects of Processing on Zearalenone
2002Zearalenone (ZEN), a common contaminant of all major cereal grains worldwide, is produced by some plant pathogenic molds including Fusarium graminearum and F. culmorum. The biological activity of this mycotoxin is mainly attributed to its estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.
Dojin, Ryu +2 more
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Occurrence of zearalenone in maize
Mycotoxin Research, 1993The occurrence of zearalenone in whole plants and parts of maize usually used for silage making was investigated during the cultivation period of the crop.Zearalenone was detected upto several hundreds of μg/kg DM, that mainly accumulated at the end of the ripening process thus contaminating the silages subsequently.
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Allyl Derivatives of Zearalenone
Journal of Pharmaceutical Sciences, 1980The Claisen rearrangement of 4-O-allylzearalenone led to only one principal product, which was identified as 3-allylzearalenone with the aid of photochemical isomerization and PMR spectroscopy. This general method is useful for distinguishing 3-substituted zearalenone isomers from 5-substituted isomers.
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